TASOR2 and RFC5

Data Source:
BioGRID (two hybrid)

		TASOR2	RFC5
Description		transcription activation suppressor family member 2	replication factor C subunit 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Nucleus Nucleoplasm DNA Replication Factor C Complex Ctf18 RFC-like Complex
	Molecular Function	Protein Binding	DNA Clamp Loader Activity Protein Binding ATP Binding Single-stranded DNA Helicase Activity Enzyme Binding
	Biological Process		DNA Replication DNA-dependent DNA Replication DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Nucleotide-excision Repair, DNA Gap Filling Translesion Synthesis Telomere Maintenance Via Semi-conservative Replication DNA Duplex Unwinding Nucleotide-excision Repair, DNA Incision Error-prone Translesion Synthesis DNA Damage Response, Detection Of DNA Damage Error-free Translesion Synthesis Positive Regulation Of DNA-directed DNA Polymerase Activity Regulation Of Signal Transduction By P53 Class Mediator
Pathways			Translesion synthesis by REV1 Recognition of DNA damage by PCNA-containing replication complex Translesion Synthesis by POLH Polymerase switching on the C-strand of the telomere Activation of ATR in response to replication stress PCNA-Dependent Long Patch Base Excision Repair Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Regulation of TP53 Activity through Phosphorylation Polymerase switching G2/M DNA damage checkpoint
Drugs
Diseases
GWAS			Metabolite levels ( 23823483) Neurociticism ( 29500382) Obesity-related traits ( 23251661) Physiological traits ( 31902109)
Interacting Genes		49 interacting genes: ARMC7 ATRIP BHLHB9 C1orf109 CARD9 CCDC33 CCDC85B CCNG2 CFAP206 COX5B CTNNA3 ERH FBF1 GPSM1 HGS HSF2BP KCTD9 KIFC3 KLHL40 LDOC1 LMO1 LONRF1 MDFI MEOX2 MID2 MKRN3 MLH1 MORN3 NEK6 PACRGL PIH1D2 PIK3R3 PNMA1 POLR1C PPP1R16B PRKAB2 PRKAR1B RFC5 SCAMP1 SERTAD3 SMARCB1 STAT3 TRIM23 TRIM42 TRIM73 TSEN15 USHBP1 YPEL3 ZNF76	35 interacting genes: ARID5A BIRC2 CCNC CHTF18 COPS6 DAPK1 DDIT4L EEF1A1 EML2 EXOSC8 FAM166B KRT34 LMO3 LRIF1 MED31 N4BP3 NAB2 NR5A1 PCNA PPP1R16B PTEN RBM48 RFC2 RFC4 SUMO2 TASOR2 TRIM38 TSNAX UNC119 XAF1 XIAP YPEL3 ZMAT1 ZNF19 ZNF426
Entrez ID		54906	5985
HPRD ID		10695	02677
Ensembl ID		ENSG00000108021	ENSG00000111445
Uniprot IDs		Q5VWN6	P40937 Q59GW7
PDB IDs			1LFS 6VVO
Enriched GO Terms of Interacting Partners?
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