NSD3 and AP3M2

Data Source:
BioGRID (biochemical)

		NSD3	AP3M2
Description		nuclear receptor binding SET domain protein 3	adaptor related protein complex 3 subunit mu 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Golgi Apparatus AP-type Membrane Coat Adaptor Complex Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Axon Cytoplasm
	Molecular Function	Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding Histone Methyltransferase Activity (H3-K36 Specific) Transcription Regulator Activator Activity
	Biological Process	Regulation Of Transcription, DNA-templated Histone H3-K36 Methylation Histone Methylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Histone H3-K36 Trimethylation	Intracellular Protein Transport Endocytosis Anterograde Axonal Transport Vesicle-mediated Transport Anterograde Synaptic Vesicle Transport
Pathways		PKMTs methylate histone lysines
Drugs
Diseases
GWAS			Blond vs. brown/black hair color ( 30531825)
Interacting Genes		42 interacting genes: AKT1 ATM BCAR3 CASP8 CBLC CBX3 CBX5 CDKN2A CHEK2 DAXX DOCK7 ESR1 ETV3 FGFR4 GLIS2 GLYR1 H1-1 H3-5 H3C1 H4C1 HOXC4 MLLT6 MNDA MYC NFIC PAX2 PPM1D RB1CC1 SEPTIN6 SLU7 SOX3 SOX4 SPAG8 STAC3 TCF3 TEAD2 TERT TGFB1 TRIM55 TRIM63 UBE2I ZNF557	1 interacting genes: MEOX2
Entrez ID		54904	10947
HPRD ID		06155	09801
Ensembl ID		ENSG00000147548	ENSG00000070718
Uniprot IDs		Q9BZ95	A0A384NYL6 P53677
PDB IDs		2DAQ 2NCZ 2ND1 4GND 4GNE 4GNF 4GNG 4RXJ 5UPD 6CEN 6G24 6G25 6G27 6G29 6G2B 6G2C 6G2E 6G2F 6G2O 6G3P 6G3T 7CRP 7CRQ 7CRR
Enriched GO Terms of Interacting Partners?
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