BCOR and PCGF1

Data Source:
BioGRID (two hybrid)

		BCOR	PCGF1
Description		BCL6 corepressor	polycomb group ring finger 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm BCOR Complex	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Corepressor Activity Ubiquitin-protein Transferase Activity Protein Binding Transcription Factor Binding Heat Shock Protein Binding Histone Deacetylase Binding	Protein Binding Protein C-terminus Binding Metal Ion Binding Promoter-specific Chromatin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Histone H3-K36 Methylation Blastocyst Hatching Heart Development Negative Regulation Of Bone Mineralization Histone H2A Monoubiquitination Odontogenesis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Histone H3-K4 Methylation Roof Of Mouth Development Specification Of Axis Polarity Negative Regulation Of Tooth Mineralization	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Silencing Regulation Of Transcription, DNA-templated Histone H2A Monoubiquitination Histone H2A-K119 Monoubiquitination
Pathways
Drugs
Diseases		Anophthalmia and microphthalmia (A/M)
GWAS		Pit-and-Fissure caries ( 23470693) Platelet count ( 29403010) Refractive error ( 32231278) Venous thromboembolism ( 31676865)
Interacting Genes		17 interacting genes: BCL6 CPNE1 CPNE2 CPNE4 HDAC1 HDAC3 HDAC4 HDAC5 HDAC6 MLLT3 NAA10 NACC1 PCGF1 PCGF3 SP1 UBTD1 USP7	12 interacting genes: BCOR CALCOCO2 CBX6 CBX7 FCHO1 MUC7 PCGF5 RNF125 RNF2 TRIM55 UBE2D3 UBE2U
Entrez ID		54880	84759
HPRD ID		06458	11404
Ensembl ID		ENSG00000183337	ENSG00000115289
Uniprot IDs		Q6W2J9	Q9BSM1
PDB IDs		2N1L 3BIM 4HPL 6B7G	4HPL 4HPM 5JH5
Enriched GO Terms of Interacting Partners?
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