ZCCHC2 and PHLPP1

Data Source:
BioGRID (affinity chromatography technology)

		ZCCHC2	PHLPP1
Description		zinc finger CCHC-type containing 2	PH domain and leucine rich repeat protein phosphatase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Cytoplasm Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Nucleic Acid Binding Zinc Ion Binding Phosphatidylinositol Binding	Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process		Regulation Of T Cell Anergy Protein Dephosphorylation Apoptotic Process Signal Transduction Entrainment Of Circadian Clock Regulation Of Apoptotic Process Regulation Of MAPK Cascade Regulation Of JNK Cascade Negative Regulation Of Protein Kinase B Signaling Regulation Of P38MAPK Cascade
Pathways			Negative regulation of the PI3K/AKT network
Drugs
Diseases
GWAS		Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Bipolar disorder ( 31043756) Breastfeeding duration ( 25475840) Chronotype ( 30696823) Depressive symptoms x dependent stressful life events interaction (1df test) ( 30718454) Depressive symptoms x dependent stressful life events interaction (2df test) ( 30718454) Menopause (age at onset) ( 29773799) Morning person ( 30696823) Pulse pressure ( 30224653) Serum albumin level ( 23022100)	Aggressiveness in attention deficit hyperactivity disorder ( 27021288) Hip circumference adjusted for BMI ( 28552196) Plateletcrit ( 32888494)
Interacting Genes			6 interacting genes: BRAP CSNK1A1 GSK3B SLC9A3R1 SUGT1 WDR48
Entrez ID		54877	23239
HPRD ID		11696	15145
Ensembl ID		ENSG00000141664	ENSG00000081913
Uniprot IDs		Q9BRD4 Q9C0B9	O60346
PDB IDs
Enriched GO Terms of Interacting Partners?
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