POLR2J3 and SATB2

Data Source:
BioGRID (two hybrid)

		POLR2J3	SATB2
Description		RNA polymerase II subunit J3	SATB homeobox 2
Image		No pdb structure
GO Annotations	Cellular Component	RNA Polymerase II, Core Complex	Histone Deacetylase Complex Chromatin Nucleoplasm Transcription Regulator Complex Nuclear Matrix
	Molecular Function	RNA Polymerase II Activity DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Protein Dimerization Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Histone Deacetylase Binding
	Biological Process	Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Osteoblast Development Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Embryonic Pattern Specification Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Cartilage Development Roof Of Mouth Development Cellular Response To Organic Substance
Pathways			SUMOylation of chromatin organization proteins RUNX2 regulates osteoblast differentiation
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Brain cytoarchitecture ( 20308991) Cerebrospinal fluid immune biomarker levels ( 32066700) Chin dimples ( 27182965) Colorectal cancer or advanced adenoma ( 30510241) FEV1 ( 30804560) Heel bone mineral density ( 30598549) Height ( 31562340) Insomnia ( 23728906) Loneliness (multivariate analysis) ( 27629369) Lung function (FVC) ( 30804560) Menarche (age at onset) ( 27182965 29773799 25231870) Rheumatoid arthritis ( 30891314) Schizophrenia ( 28991256 25056061 29483656 30285260) Type 2 diabetes ( 25760438) Ulcerative colitis ( 20228799) Waist circumference ( 23966867)
Interacting Genes		6 interacting genes: ATPAF2 POLR1C SATB2 TRAF4 TTC23 VPS37C	5 interacting genes: HDAC1 MTA2 PIAS1 POLR2J3 RAB3IL1
Entrez ID		548644	23314
HPRD ID		18684	12178
Ensembl ID		ENSG00000168255	ENSG00000119042
Uniprot IDs		A0A0B4J2F8 Q9GZM3	A0A024R3U6 B3KPQ9 Q59FT3 Q9UPW6
PDB IDs			1WI3 1WIZ 2CSF
Enriched GO Terms of Interacting Partners?
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