SATB2

Description		SATB homeobox 2
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GO Annotations	Cellular Component	Histone Deacetylase Complex Chromatin Nucleoplasm Transcription Regulator Complex Nuclear Matrix
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Histone Deacetylase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Osteoblast Development Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Embryonic Pattern Specification Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Cartilage Development Roof Of Mouth Development Cellular Response To Organic Substance
Pathways		SUMOylation of chromatin organization proteins RUNX2 regulates osteoblast differentiation
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Brain cytoarchitecture ( 20308991) Cerebrospinal fluid immune biomarker levels ( 32066700) Chin dimples ( 27182965) Colorectal cancer or advanced adenoma ( 30510241) FEV1 ( 30804560) Heel bone mineral density ( 30598549) Height ( 31562340) Insomnia ( 23728906) Loneliness (multivariate analysis) ( 27629369) Lung function (FVC) ( 30804560) Menarche (age at onset) ( 27182965 29773799 25231870) Rheumatoid arthritis ( 30891314) Schizophrenia ( 28991256 25056061 29483656 30285260) Type 2 diabetes ( 25760438) Ulcerative colitis ( 20228799) Waist circumference ( 23966867)
Novel Interacting Genes		2 novel interacting genes: ABI2 ADAM23
Interacting Genes		5 interacting genes: HDAC1 MTA2 PIAS1 POLR2J3 RAB3IL1
Entrez ID		23314
HPRD ID		12178
Ensembl ID		ENSG00000119042
Uniprot IDs		A0A024R3U6 B3KPQ9 Q59FT3 Q9UPW6
PDB IDs		1WI3 1WIZ 2CSF
Enriched GO Terms of Interacting Partners?
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