FBXL12 and MARCHF2

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)

		FBXL12	MARCHF2
Description		F-box and leucine rich repeat protein 12	membrane associated ring-CH-type finger 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol SCF Ubiquitin Ligase Complex	Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endosome Membrane Integral Component Of Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Protein Polyubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Entrainment Of Circadian Clock By Photoperiod Post-translational Protein Modification Regulation Of Cell Cycle	Endocytosis Protein Ubiquitination
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Pursuit maintenance gain ( 29064472)
Interacting Genes		19 interacting genes: A2M ALDH3A1 APOE CDC37 CDKN1C DOCK8 ECSIT FBF1 FXYD3 GEMIN4 LNX1 MAST1 PSEN1 PSEN2 PSME3 RNF32 SMAD1 TGFBR1 UBE2D3	30 interacting genes: AQP6 CCL4 CD79A CDC34 CFTR CREB3L1 ERGIC3 F11R FAM209A FATE1 GJA8 GPX8 KASH5 LDLRAD1 LGR4 MUC1 PEX12 PLPPR2 SCN3B SSMEM1 STX6 SYNE4 TMEM106C TMEM179B TMEM52B TMEM86B TSPAN12 TSPO2 UBE2D1 UBE2H
Entrez ID		54850	51257
HPRD ID		12363	14361
Ensembl ID		ENSG00000127452	ENSG00000099785
Uniprot IDs		Q9NXK8	Q9P0N8
PDB IDs
Enriched GO Terms of Interacting Partners?
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