MBTD1 and EPC1

Data Source:
BioGRID (affinity chromatography technology, pull down)

		MBTD1	EPC1
Description		mbt domain containing 1	enhancer of polycomb homolog 1
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GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Nuclear Membrane Piccolo NuA4 Histone Acetyltransferase Complex NuA4 Histone Acetyltransferase Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Chromatin Binding Protein Binding Zinc Ion Binding Methylated Histone Binding Histone Binding	Histone Acetyltransferase Activity Protein Binding
	Biological Process	Chromatin Organization Negative Regulation Of Transcription, DNA-templated Embryonic Skeletal System Development	Negative Regulation Of Transcription By RNA Polymerase II Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Vascular Associated Smooth Muscle Cell Differentiation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G0 To G1 Transition
Pathways			HATs acetylate histones Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Coronary artery disease ( 33020668)	Diastolic blood pressure ( 30224653) Metabolite levels ( 23823483) Platelet distribution width ( 32888494 27863252) Sexual dysfunction (female) ( 22509378)
Interacting Genes		3 interacting genes: EPC1 H4C1 TULP3	9 interacting genes: CHRM5 E2F6 HOPX KAT5 KRT15 MBTD1 RINT1 SYCE1L TRIM27
Entrez ID		54799	80314
HPRD ID		14369	09941
Ensembl ID		ENSG00000011258	ENSG00000120616
Uniprot IDs		Q05BQ5	Q9H2F5
PDB IDs		3FEO 4C5I 6NFX	6NFX
Enriched GO Terms of Interacting Partners?
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