POU4F3 and DUSP21

Data Source:
BioGRID (two hybrid)

		POU4F3	DUSP21
Description		POU class 4 homeobox 3	dual specificity phosphatase 21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm	Nucleus Cytoplasm Mitochondrial Matrix Extrinsic Component Of Mitochondrial Inner Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Tyrosine Phosphatase Activity Protein Binding MAP Kinase Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Visual Perception Sensory Perception Of Sound Vestibulocochlear Nerve Development Retinal Ganglion Cell Axon Guidance Inner Ear Morphogenesis Inner Ear Auditory Receptor Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Axon Extension Neuromuscular Process Controlling Balance Neuron Apoptotic Process	Inactivation Of MAPK Activity Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases		Deafness, autosomal dominant
GWAS		PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		7 interacting genes: AURKA DUSP21 GOLGA2 KRT31 KRTAP6-3 NHLRC4 PLA2G10	33 interacting genes: APP ATP23 BPIFA1 CPNE7 CTBP2 EPHA3 EPHA5 ERBB3 ERBB4 EYA2 FAAP20 GET4 GORASP2 IGF1R KLHL20 KRT33B KRTAP11-1 MAP2K5 MYO15B OIP5 POU4F3 PTK7 RFX6 RGS2 ROR1 ROR2 SUOX TEX11 TOX3 TRAF1 UBQLN2 USP2 ZMAT1
Entrez ID		5459	63904
HPRD ID		03911	06494
Ensembl ID		ENSG00000091010	ENSG00000189037
Uniprot IDs		Q15319	Q9H596
PDB IDs
Enriched GO Terms of Interacting Partners?
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