POU4F2 and KRTAP4-11

Data Source:
BioGRID (two hybrid)

		POU4F2	KRTAP4-11
Description		POU class 4 homeobox 2	keratin associated protein 4-11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Euchromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Nuclear Speck	Cytosol Keratin Filament
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific P53 Binding Protein Binding Promoter-specific Chromatin Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II MAPK Cascade Regulation Of Transcription By RNA Polymerase II Spermatogenesis Axon Guidance Heart Development Sensory Perception Of Sound Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Neuron Differentiation Intracellular Estrogen Receptor Signaling Pathway Retinal Ganglion Cell Axon Guidance Cellular Response To Insulin Stimulus Positive Regulation Of Programmed Cell Death Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Cell Differentiation Positive Regulation Of Cell Differentiation Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Axon Extension Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Glucose Import Axon Extension Neuromuscular Process Controlling Balance Regulation Of DNA-binding Transcription Factor Activity Retina Development In Camera-type Eye Cellular Response To Cytokine Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Oxygen Levels Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Retinal Ganglion Cell Axon Guidance Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Amacrine Cell Differentiation Negative Regulation Of Adipose Tissue Development Dorsal Root Ganglion Development Positive Regulation Of Transcription Regulatory Region DNA Binding	Keratinization
Pathways		Regulation of TP53 Activity through Association with Co-factors	Keratinization
Drugs
Diseases
GWAS		Malaria ( 31844061) Metabolite levels ( 23823483)
Interacting Genes		75 interacting genes: ADAMTSL4 ALPP CCN3 CD46 CERCAM CHIC2 CHRD CHRDL2 COL8A1 CYP21A2 CYSRT1 DLX3 ESR1 FAM86C1P GRN HDHD3 HIGD2B IGFBP6 IGFL1 INCA1 KPRP KRT31 KRT35 KRT38 KRT83 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP13-1 KRTAP13-3 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1C LCE1F LCE5A LCN2 LGALS13 LHX2 LYPD2 MMADHC NFKBID NOTO PCSK5 PLSCR2 RBP3 RBPMS RGS19 SPRY4 TGFB1 TRIM42 VWC2	70 interacting genes: ADAMTSL4 CATSPER1 CRCT1 CYSRT1 DHRS1 EHHADH ENKD1 EPDR1 FAM221A FAM76B FBXO34 GATA1 GLRX3 GNE GRAP2 HOXA1 KLHL38 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP15-1 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-3 KRTAP5-9 KRTAP6-2 KRTAP9-2 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2C LCE3A LCE3B LCE3C LCE3E LCE4A LCE5A LELP1 MEOX2 NBPF19 NOTCH2NLA NR4A3 NUFIP2 OTX1 P4HB PLSCR1 POTEB3 POU4F2 PRPF31 RGS17 SHFL SLC23A1 SMCP SPRY2 TGFB1 TSPAN4 VASN VGLL3 ZNF417 ZNF552 ZNF837
Entrez ID		5458	653240
HPRD ID		00220
Ensembl ID		ENSG00000151615	ENSG00000212721
Uniprot IDs		Q12837	Q9BYQ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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