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ZFAND6 and DNM2
Data Source:
HPRD
(two hybrid)
ZFAND6
DNM2
Description
zinc finger AN1-type containing 6
dynamin 2
Image
No pdb structure
GO Annotations
Cellular Component
Cellular_component
Cytosol
Golgi Membrane
Phagocytic Cup
Nucleus
Cytoplasm
Endosome
Golgi Apparatus
Trans-Golgi Network
Centrosome
Cytosol
Microtubule
Plasma Membrane
Clathrin-coated Pit
Focal Adhesion
Postsynaptic Density
Microtubule Cytoskeleton
Membrane
Lamellipodium
Axon
Growth Cone
Midbody
Endocytic Vesicle Membrane
Phagocytic Vesicle Membrane
Cytoplasmic Vesicle
Mitochondrial Membrane
Ruffle Membrane
Protein-containing Complex
Dendritic Spine Head
Postsynaptic Membrane
Clathrin-coated Endocytic Vesicle
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Presynapse
Postsynaptic Endocytic Zone Membrane
Glutamatergic Synapse
Postsynaptic Density, Intracellular Component
Molecular Function
Molecular_function
DNA Binding
Protein Binding
Zinc Ion Binding
Polyubiquitin Modification-dependent Protein Binding
GTPase Activity
Protein Binding
GTP Binding
Microtubule Binding
SH3 Domain Binding
Enzyme Binding
Protein Kinase Binding
D2 Dopamine Receptor Binding
Phosphatidylinositol 3-kinase Regulatory Subunit Binding
Protein-containing Complex Binding
WW Domain Binding
Nitric-oxide Synthase Binding
Biological Process
Protein Targeting To Peroxisome
Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Response To Tumor Necrosis Factor
G2/M Transition Of Mitotic Cell Cycle
Mitochondrial Fission
G Protein-coupled Receptor Internalization
Dynamin Family Protein Polymerization Involved In Mitochondrial Fission
Regulation Of Transcription, DNA-templated
Golgi To Plasma Membrane Transport
Endocytosis
Receptor-mediated Endocytosis
Phagocytosis
Signal Transduction
Spermatogenesis
Response To Light Stimulus
Positive Regulation Of Lamellipodium Assembly
Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Axon Extension
Receptor Internalization
Transferrin Transport
Regulation Of Rac Protein Signal Transduction
Response To Cocaine
Positive Regulation Of Apoptotic Process
Macropinocytosis
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Synaptic Vesicle Transport
Neuron Projection Morphogenesis
Positive Regulation Of Phagocytosis
Regulation Of Synapse Structure Or Activity
Regulation Of Nitric-oxide Synthase Activity
Membrane Organization
Membrane Fusion
Cellular Response To Carbon Monoxide
Cellular Response To X-ray
Cellular Response To Nitric Oxide
Postsynaptic Neurotransmitter Receptor Internalization
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Negative Regulation Of Non-motile Cilium Assembly
Cellular Response To Dopamine
Regulation Of Golgi Organization
Positive Regulation Of Sodium:potassium-exchanging ATPase Activity
Negative Regulation Of Membrane Tubulation
Positive Regulation Of Clathrin-dependent Endocytosis
Pathways
Peroxisomal protein import
Peroxisomal protein import
Toll Like Receptor 4 (TLR4) Cascade
Retrograde neurotrophin signalling
Gap junction degradation
Formation of annular gap junctions
NOSTRIN mediated eNOS trafficking
MHC class II antigen presentation
Lysosome Vesicle Biogenesis
Golgi Associated Vesicle Biogenesis
Recycling pathway of L1
Clathrin-mediated endocytosis
NGF-stimulated transcription
Drugs
Diseases
Centronuclear myopathy
Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS
Eosinophil counts (
29403010
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Immature fraction of reticulocytes (
32888494
)
Monocyte count (
29403010
)
Reticulocyte count (
32888494
27863252
)
Reticulocyte fraction of red cells (
32888494
27863252
)
Type 2 diabetes (
20581827
)
White blood cell count (
29403010
)
Bipolar disorder (
31043756
)
Height (
25429064
)
Hyperlipidemia (time to event) (
32589924
)
LDL cholesterol (
21347282
)
Interacting Genes
7 interacting genes:
CDC34
DNM2
PKN1
RAD23A
TRAF2
TRAF5
UBC
68 interacting genes:
AMPH
AOC1
AP2A1
APP
APPL1
ATF7IP
ATXN3
BAG3
BIN1
CCDC90B
CCR5
CCT7
CDK1
CTTN
DDX39B
DNM1
DYNC1I1
DYNLL1
EIF3L
EPS15
FLAD1
FNBP1L
GDF9
GOLGA2
GRAP2
GRB2
HCK
HMGB1
ITSN1
KDR
MAN1B1
MANEA
MPHOSPH6
NTAQ1
PALS2
PDE6G
PFN1
PPIB
PRKAA2
PSTPIP1
PTK2
PYGM
QARS1
RHOU
RNF8
RPS2
RWDD2B
SDCBP
SEC23A
SH3GL2
SH3GLB1
SH3RF1
SHANK1
SHANK2
SNAPIN
SNX9
SPRY2
SRC
TIAM2
TRAF4
TRIP10
TYK2
UBASH3A
VAV1
WBP4
XIAP
ZBTB16
ZFAND6
Entrez ID
54469
1785
HPRD ID
18314
03852
Ensembl ID
ENSG00000086666
ENSG00000079805
Uniprot IDs
Q6FIF0
P50570
Q8N1K8
PDB IDs
2YS1
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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