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POLR2L and NACC1
Data Source:
BioGRID
(two hybrid)
POLR2L
NACC1
Description
RNA polymerase II, I and III subunit L
nucleus accumbens associated 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
RNA Polymerase II, Core Complex
RNA Polymerase III Complex
RNA Polymerase I Complex
Cytosol
Nucleus
Nucleoplasm
Cytoplasm
Cell Junction
Intracellular Membrane-bounded Organelle
Molecular Function
DNA Binding
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Zinc Ion Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Protein Binding
Histone Deacetylase Binding
Biological Process
MRNA Splicing, Via Spliceosome
Transcription-coupled Nucleotide-excision Repair
Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase I
Transcription By RNA Polymerase I
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Fibroblast Growth Factor Receptor Signaling Pathway
RNA Metabolic Process
Positive Regulation Of Type I Interferon Production
Somatic Stem Cell Population Maintenance
SnRNA Transcription By RNA Polymerase II
TRNA Transcription By RNA Polymerase III
Positive Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Viral Transcription
Regulation Of Gene Silencing By MiRNA
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Transcription, DNA-templated
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
Cytosolic sensors of pathogen-associated DNA
MicroRNA (miRNA) biogenesis
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
Transcriptional regulation by small RNAs
PIWI-interacting RNA (piRNA) biogenesis
Activation of anterior HOX genes in hindbrain development during early embryogenesis
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase III Chain Elongation
RNA Polymerase I Transcription Termination
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Inhibition of DNA recombination at telomere
Drugs
Diseases
GWAS
Pulse pressure (
30578418
)
Obesity-related traits (
23251661
)
Interacting Genes
28 interacting genes:
AGR2
BANP
CCDC85B
CCN3
CHEK2
COIL
EXOSC5
FAM217B
L3MBTL3
NACC1
NFKBIB
PHC2
POLR2A
POLR2B
POLR2C
POLR2D
POLR2E
POLR2G
POLR2H
PSMA6
REL
RPAP1
SNX7
SPAG5
THAP1
TP53BP2
TRIP13
ZBTB14
19 interacting genes:
BCOR
C8orf33
EHHADH
ELOA
HDAC3
HDAC4
LGALS8
LSM3
PML
POLR2L
PRKCI
PRPF18
PRPF3
SENP1
SENP2
TARDBP
UBE2I
UBTFL1
ZNF512B
Entrez ID
5441
112939
HPRD ID
01155
10692
Ensembl ID
ENSG00000177700
ENSG00000160877
Uniprot IDs
P62875
A0A024R7E0
Q96RE7
PDB IDs
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6DRD
6O9L
3GA1
4U2N
Enriched GO Terms of Interacting Partners
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