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POLR2D and ZSCAN1
Data Source:
BioGRID
(two hybrid)
POLR2D
ZSCAN1
Description
RNA polymerase II subunit D
zinc finger and SCAN domain containing 1
Image
No pdb structure
GO Annotations
Cellular Component
P-body
Nucleus
Nucleoplasm
RNA Polymerase II, Core Complex
Cytosol
Nuclear Speck
Chromatin
Nucleus
Molecular Function
Nucleotide Binding
Single-stranded DNA Binding
Single-stranded RNA Binding
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Translation Initiation Factor Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
MRNA Splicing, Via Spliceosome
Transcription-coupled Nucleotide-excision Repair
Transcription, DNA-templated
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Fibroblast Growth Factor Receptor Signaling Pathway
RNA Metabolic Process
MRNA Export From Nucleus In Response To Heat Stress
Recruitment Of 3'-end Processing Factors To RNA Polymerase II Holoenzyme Complex
Somatic Stem Cell Population Maintenance
SnRNA Transcription By RNA Polymerase II
Positive Regulation Of Translational Initiation
Positive Regulation Of Viral Transcription
Regulation Of Gene Silencing By MiRNA
Regulation Of Transcription By RNA Polymerase II
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
MicroRNA (miRNA) biogenesis
Transcriptional regulation by small RNAs
PIWI-interacting RNA (piRNA) biogenesis
Activation of anterior HOX genes in hindbrain development during early embryogenesis
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Inhibition of DNA recombination at telomere
Drugs
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
HDL cholesterol levels (
32203549
)
Interacting Genes
16 interacting genes:
ATF7IP
EMX1
ESR1
HOXC9
IKBKG
NR5A2
POLR2A
POLR2B
POLR2C
POLR2E
POLR2G
POLR2H
POLR2K
POLR2L
TRIM29
ZSCAN1
40 interacting genes:
ANKRD55
APP
ASH2L
ATXN1
CDC5L
CDK6
CNOT6L
ERCC3
FXR2
GOPC
GTF2E1
GTF2H1
HOPX
INSM2
MED21
MED31
MED7
NFYC
NPAS2
PLRG1
POLR2B
POLR2D
POLR2E
PPARG
PPL
RFC1
SH2D2A
SNW1
SSX3
SSX5
TAF7
TBX20
TIMELESS
TRIM31
TTF2
ZKSCAN5
ZNF263
ZNF396
ZNF407
ZSCAN22
Entrez ID
5433
284312
HPRD ID
16191
15897
Ensembl ID
ENSG00000144231
ENSG00000152467
Uniprot IDs
O15514
Q8NBB4
PDB IDs
2C35
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6DRD
6O9L
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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