ZSCAN1 and TRIM31

Data Source:
BioGRID (two hybrid)

		ZSCAN1	TRIM31
Description		zinc finger and SCAN domain containing 1	tripartite motif containing 31
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Cytoplasm Mitochondrion Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Regulation Of Gene Expression Protein Ubiquitination Negative Regulation Of Viral Transcription Innate Immune Response Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Regulation Of Viral Release From Host Cell
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS			Anger ( 24489884) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Beta-2 microglubulin plasma levels ( 23417110) Blood protein levels ( 28240269) Estimated glomerular filtration rate in diabetes ( 31451708) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Isovolumetric relaxation time ( 28394258) Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular hemoglobin ( 27863252) Neuroticism ( 29255261) Prostate cancer ( 25217961) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Type 1 diabetes and autoimmune thyroid diseases ( 25936594)
Interacting Genes		40 interacting genes: ANKRD55 APP ASH2L ATXN1 CDC5L CDK6 CNOT6L ERCC3 FXR2 GOPC GTF2E1 GTF2H1 HOPX INSM2 MED21 MED31 MED7 NFYC NPAS2 PLRG1 POLR2B POLR2D POLR2E PPARG PPL RFC1 SH2D2A SNW1 SSX3 SSX5 TAF7 TBX20 TIMELESS TRIM31 TTF2 ZKSCAN5 ZNF263 ZNF396 ZNF407 ZSCAN22	22 interacting genes: CCT6A EID3 IKBKG MAGEA1 MAGEA2B MKRN3 MNAT1 NLRP3 NSMCE4A TRAF2 TRIM23 TRIM27 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E2 UBE2K UBE2L3 UBE2W USP7 ZSCAN1
Entrez ID		284312	11074
HPRD ID		15897	10281
Ensembl ID		ENSG00000152467	ENSG00000204616
Uniprot IDs		Q8NBB4	Q2L6J1 Q9BZY9
PDB IDs			2YSJ 2YSL
Enriched GO Terms of Interacting Partners?
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