CHRAC1 and SMARCA5

Data Source:
HPRD (in vivo)

		CHRAC1	SMARCA5
Description		chromatin accessibility complex subunit 1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Epsilon DNA Polymerase Complex CHRAC	Condensed Chromosome Fibrillar Center Nucleus Nucleoplasm Chromatin Silencing Complex Cytosol NURF Complex RSF Complex Intracellular Membrane-bounded Organelle Nuclear Replication Fork
	Molecular Function	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Protein Heterodimerization Activity	DNA Binding Helicase Activity Protein Binding ATP Binding DNA-dependent ATPase Activity ATPase Activity Nucleosome Binding Histone Binding
	Biological Process	Chromatin Remodeling DNA Biosynthetic Process	RDNA Heterochromatin Assembly Nucleosome Assembly Chromatin Remodeling DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Nucleosome Positioning CENP-A Containing Nucleosome Assembly ATP-dependent Chromatin Remodeling Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Leukemia Inhibitory Factor
Pathways			NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Deposition of new CENPA-containing nucleosomes at the centromere
Drugs			Beta-D-Glucose 4-Deoxy-Alpha-D-Glucose
Diseases
GWAS		Experiencing mood swings ( 29500382)	Height ( 31562340) Malaria ( 31844061)
Interacting Genes		5 interacting genes: APP BAZ1A FAM9B POLE3 SMARCA5	18 interacting genes: BAZ1A BAZ1B BAZ2A CDT1 CHRAC1 CREB1 CTNNB1 DNMT3B H3-3A H3C1 H4-16 HDAC2 MAF POLE3 PTEN RAD21 RSF1 SATB1
Entrez ID		54108	8467
HPRD ID		06275	04538
Ensembl ID		ENSG00000104472	ENSG00000153147
Uniprot IDs		Q9NRG0	O60264
PDB IDs			6NE3
Enriched GO Terms of Interacting Partners?
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