CNTN5 and FDX1

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)

		CNTN5	FDX1
Description		contactin 5	ferredoxin 1
Image
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane GABA-ergic Synapse Anchored Component Of Presynaptic Membrane	Mitochondrion Mitochondrial Matrix
	Molecular Function		Iron Ion Binding Electron Transfer Activity 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Cell Adhesion Sensory Perception Of Sound Presynapse Assembly	C21-steroid Hormone Biosynthetic Process Cholesterol Metabolic Process Sterol Metabolic Process Electron Transport Chain Hormone Biosynthetic Process Small Molecule Metabolic Process Cellular Response To CAMP Cellular Response To Forskolin
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Mitochondrial iron-sulfur cluster biogenesis Pregnenolone biosynthesis Endogenous sterols Electron transport from NADPH to Ferredoxin Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)
Drugs			Mitotane
Diseases
GWAS		Alcohol dependence ( 26365420) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Asthma ( 29273806) Atrial fibrillation ( 17903304) Behcet's disease ( 27548383) Bipolar disorder and schizophrenia ( 20889312) Blood protein levels ( 30072576 29875488 28240269) Bone mineral density (femoral neck) ( 26911590) Cardiorespiratory fitness (800m run time) ( 32572135) Carotid intima media thickness x smoking interaction ( 32117412) Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Chronotype ( 30696823) Diastolic blood pressure ( 27841878) Factor VII activity ( 30642921) Feeling miserable ( 29500382) Fructosamine levels ( 29844224) Glycated hemoglobin levels ( 28898252) Gout vs. Hyperuricemia ( 31289104) Immune reponse to smallpox (secreted IL-2) ( 22610502) Loneliness (multivariate analysis) ( 27629369) Myopia (pathological) ( 23049088) Neurological blood protein biomarker levels ( 31320639) Obesity-related traits ( 23251661) Objective response to lithium treatment in bipolar disorder ( 26503763) Plasma kynurenine levels in major depressive disorder ( 29317604) Spatial memory ( 31596458) Total glycated albumin levels ( 29844224) Volumetric brain MRI ( 17903297) Waist-hip ratio ( 25673412)	Cognitive function ( 24684796) Coronary artery disease ( 32469254)
Interacting Genes			5 interacting genes: CYCS CYP11A1 CYP11B2 FDXR PRKAB2
Entrez ID		53942	2230
HPRD ID		06241	00059
Ensembl ID		ENSG00000149972	ENSG00000137714
Uniprot IDs		O94779	P10109
PDB IDs		4N68 5E52	3N9Y 3N9Z 3NA0 3NA1 3P1M
Enriched GO Terms of Interacting Partners?
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