Wiki-MPM

  • About
  • Search
  • Browse
  • People
  • Funding
  • Updates

FDX1

Description ferredoxin 1
Image
GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Matrix
Molecular Function
  • Iron Ion Binding
  • Electron Transfer Activity
  • 2 Iron, 2 Sulfur Cluster Binding
Biological Process
  • C21-steroid Hormone Biosynthetic Process
  • Cholesterol Metabolic Process
  • Sterol Metabolic Process
  • Electron Transport Chain
  • Hormone Biosynthetic Process
  • Small Molecule Metabolic Process
  • Cellular Response To CAMP
  • Cellular Response To Forskolin
Pathways
  • Mitochondrial iron-sulfur cluster biogenesis
  • Pregnenolone biosynthesis
  • Endogenous sterols
  • Electron transport from NADPH to Ferredoxin
  • Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)
Drugs
  • Mitotane
Diseases
GWAS
  • Cognitive function ( 24684796)
  • Coronary artery disease ( 32469254)
Novel Interacting Genes 7 novel interacting genes: BIRC2 BIRC3 CNTN5 CORO2A LILRB2 PBRM1 RDH5
Interacting Genes 5 interacting genes: CYCS CYP11A1 CYP11B2 FDXR PRKAB2
Entrez ID 2230
HPRD ID 00059
Ensembl ID ENSG00000137714
Uniprot IDs P10109
PDB IDs 3N9Y 3N9Z 3NA0 3NA1 3P1M
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025