CLIC5 and PTK7

Data Source:
BioGRID (affinity chromatography technology)

		CLIC5	PTK7
Description		chloride intracellular channel 5	protein tyrosine kinase 7 (inactive)
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GO Annotations	Cellular Component	Golgi Apparatus Microtubule Organizing Center Cell Cortex Actin Cytoskeleton Apical Plasma Membrane Chloride Channel Complex Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion
	Molecular Function	Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding	Protein Kinase Activity Protein Binding ATP Binding Cell Adhesion Molecule Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway
	Biological Process	Glutathione Metabolic Process Chloride Transport Female Pregnancy Visual Perception Sensory Perception Of Sound Regulation Of Ion Transmembrane Transport Response To Stimulus Chloride Transmembrane Transport	Establishment Of Planar Polarity Kidney Development Ventricular Septum Development Axis Elongation Protein Phosphorylation Cell Adhesion Signal Transduction Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Reorganization Wound Healing Establishment Of Epithelial Cell Apical/basal Polarity Convergent Extension Lung-associated Mesenchyme Development Regulation Of Canonical Wnt Signaling Pathway Coronary Vasculature Development Cellular Response To Retinoic Acid Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Blood protein levels ( 30072576 29875488) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Gout (normal type) ( 32238385) Heel bone mineral density ( 30598549) Intraocular pressure ( 29785010) Itch intensity from mosquito bite ( 28199695) Mosquito bite size ( 28199695) Periodontal microbiota ( 22699663)	Coronary artery disease ( 29212778)
Interacting Genes		8 interacting genes: ACTA1 ACTN1 EZR GSN IQGAP1 LAMTOR5 SRPK1 TPRN	38 interacting genes: CDC14A CLNK CTDSP2 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 DUSP29 ERBB2 ILKAP KRTAP1-3 KRTAP10-8 MDFI MTMR1 MTMR10 MTMR6 MTMR9 MTUS2 NBPF19 NOTCH2NLA PPM1A PPM1B PPM1F PPM1K PPP3CA PPP3CB PTEN PTPN11 PTPN12 PTPN6 PTPN7 PTPRR STYX TPTE TPTE2
Entrez ID		53405	5754
HPRD ID		06292	03534
Ensembl ID		ENSG00000112782	ENSG00000112655
Uniprot IDs		Q49AE1 Q53G01 Q9NZA1	Q13308
PDB IDs		6Y2H	6VG3
Enriched GO Terms of Interacting Partners?
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