PIP4K2A and GSTK1

Data Source:
BioGRID (two hybrid)

		PIP4K2A	GSTK1
Description		phosphatidylinositol-5-phosphate 4-kinase type 2 alpha	glutathione S-transferase kappa 1
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GO Annotations	Cellular Component	Nucleoplasm Lysosome Autophagosome Cytosol Plasma Membrane	Mitochondrion Mitochondrial Matrix Peroxisome Peroxisomal Matrix Cytosol Membrane Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidylinositol-5-phosphate 4-kinase Activity Protein Homodimerization Activity	Glutathione Transferase Activity Glutathione Peroxidase Activity Protein Binding
	Biological Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Regulation Of Autophagy Regulation Of Phosphatidylinositol 3-kinase Signaling Megakaryocyte Development Negative Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol Phosphorylation Autophagosome-lysosome Fusion Vesicle-mediated Cholesterol Transport Negative Regulation Of 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate Biosynthetic Process Positive Regulation Of Autophagosome Assembly	Protein Targeting To Peroxisome Glutathione Metabolic Process Epithelial Cell Differentiation Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process
Pathways		Synthesis of PIPs at the plasma membrane PI5P Regulates TP53 Acetylation PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Synthesis of PIPs in the nucleus	Glutathione conjugation Peroxisomal protein import Peroxisomal protein import
Drugs			Glutathione GLUTATHIONE SULFINATE
Diseases
GWAS		Acute lymphoblastic leukemia (B-cell precursor) ( 23996088) Acute lymphoblastic leukemia (childhood) ( 29348612) Acute lymphoblastic leukemia in childhood (B cell precursor) ( 29632299) B-cell acute lymphoblastic leukaemia ( 31767839) Height ( 31562340) Lymphocyte percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Positive urgency ( 30718321) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		6 interacting genes: BTK GSTK1 MEIS3 RAC1 RPS6KB1 TEC	7 interacting genes: CCNDBP1 FAM9B GRB2 KRT27 PEX5 PIP4K2A PRPF19
Entrez ID		5305	373156
HPRD ID		11931	13613
Ensembl ID		ENSG00000150867	ENSG00000197448
Uniprot IDs		P48426	Q6FII1 Q9Y2Q3
PDB IDs		2YBX 6OSP	1YZX 3RPN 3RPP
Enriched GO Terms of Interacting Partners?
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