GSTK1 and PIP4K2A

Data Source:
BioGRID (two hybrid)

		GSTK1	PIP4K2A
Description		glutathione S-transferase kappa 1	phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Peroxisome Peroxisomal Matrix Cytosol Membrane Extracellular Exosome	Nucleoplasm Lysosome Autophagosome Cytosol Plasma Membrane
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Protein Binding	Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidylinositol-5-phosphate 4-kinase Activity Protein Homodimerization Activity
	Biological Process	Protein Targeting To Peroxisome Glutathione Metabolic Process Epithelial Cell Differentiation Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Regulation Of Autophagy Regulation Of Phosphatidylinositol 3-kinase Signaling Megakaryocyte Development Negative Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol Phosphorylation Autophagosome-lysosome Fusion Vesicle-mediated Cholesterol Transport Negative Regulation Of 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate Biosynthetic Process Positive Regulation Of Autophagosome Assembly
Pathways		Glutathione conjugation Peroxisomal protein import Peroxisomal protein import	Synthesis of PIPs at the plasma membrane PI5P Regulates TP53 Acetylation PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Synthesis of PIPs in the nucleus
Drugs		Glutathione GLUTATHIONE SULFINATE
Diseases
GWAS			Acute lymphoblastic leukemia (B-cell precursor) ( 23996088) Acute lymphoblastic leukemia (childhood) ( 29348612) Acute lymphoblastic leukemia in childhood (B cell precursor) ( 29632299) B-cell acute lymphoblastic leukaemia ( 31767839) Height ( 31562340) Lymphocyte percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Positive urgency ( 30718321) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		7 interacting genes: CCNDBP1 FAM9B GRB2 KRT27 PEX5 PIP4K2A PRPF19	6 interacting genes: BTK GSTK1 MEIS3 RAC1 RPS6KB1 TEC
Entrez ID		373156	5305
HPRD ID		13613	11931
Ensembl ID		ENSG00000197448	ENSG00000150867
Uniprot IDs		Q6FII1 Q9Y2Q3	P48426
PDB IDs		1YZX 3RPN 3RPP	2YBX 6OSP
Enriched GO Terms of Interacting Partners?
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