PI4KA and SNX9

Data Source:
BioGRID (pull down)

		PI4KA	SNX9
Description		phosphatidylinositol 4-kinase alpha	sorting nexin 9
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Viral Replication Complex Golgi-associated Vesicle Membrane Extracellular Exosome	Ruffle Cytoplasm Trans-Golgi Network Cytosol Plasma Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Cytoplasmic Vesicle Cuticular Plate Extracellular Exosome
	Molecular Function	1-phosphatidylinositol 4-kinase Activity Protein Binding ATP Binding Kinase Activity Cadherin Binding Phosphatidylinositol Kinase Activity	Protein Binding 1-phosphatidylinositol Binding Ubiquitin Protein Ligase Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Arp2/3 Complex Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Signal Transduction Phosphorylation Viral RNA Genome Replication Multi-organism Membrane Organization Viral Replication Complex Formation And Maintenance Phosphatidylinositol Phosphorylation Phosphatidylinositol-mediated Signaling	Mitotic Cytokinesis Intracellular Protein Transport Endocytosis Receptor-mediated Endocytosis Endosomal Transport Positive Regulation Of Actin Filament Polymerization Cleavage Furrow Formation Positive Regulation Of GTPase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Membrane Protein Ectodomain Proteolysis Lipid Tube Assembly Membrane Organization Protein-containing Complex Assembly Plasma Membrane Tubulation
Pathways		Synthesis of PIPs at the ER membrane Synthesis of PIPs at the Golgi membrane	Golgi Associated Vesicle Biogenesis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Fulminant type 1 diabetes ( 30552108) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494)	Borderline personality disorder ( 28632202) Heart rate response to beta blockers ( 29478026) Lipoprotein (a) - cholesterol levels ( 25575512) Metabolite levels ( 23823483) Platelet distribution width ( 32888494 27863252)
Interacting Genes		10 interacting genes: C8orf33 CD4 CD7 LCK MRPL44 MTNR1B PITPNA SNX9 STRN4 TNNT1	23 interacting genes: ADAM15 ADAM9 AP1G1 CLTC DAPK1 DNM1 DNM2 EGFR FASLG ITCH KHDRBS1 LRRK1 MPHOSPH6 PAK2 PALS2 PI4KA PIK3CA PIK3R5 SOS1 SOS2 TNK2 WAS WASL
Entrez ID		5297	51429
HPRD ID		08972	12072
Ensembl ID		ENSG00000241973	ENSG00000130340
Uniprot IDs		B4DYG5 P42356 Q4LE69	Q9Y5X1
PDB IDs		6BQ1	2RAI 2RAJ 2RAK 3DYT 3DYU 3LGE
Enriched GO Terms of Interacting Partners?
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