PHKG2 and PHKG1

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		PHKG2	PHKG1
Description		phosphorylase kinase catalytic subunit gamma 2	phosphorylase kinase catalytic subunit gamma 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Phosphorylase Kinase Complex	Cytosol Phosphorylase Kinase Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Phosphorylase Kinase Activity Protein Binding Calmodulin Binding ATP Binding Tau-protein Kinase Activity	Phosphorylase Kinase Activity Calmodulin Binding ATP Binding Enzyme Binding Tau-protein Kinase Activity Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Glycogen Metabolic Process Glycogen Biosynthetic Process Glycogen Catabolic Process Generation Of Precursor Metabolites And Energy Protein Phosphorylation Positive Regulation Of Glycogen Catabolic Process	Carbohydrate Metabolic Process Glycogen Biosynthetic Process Glycogen Catabolic Process Protein Phosphorylation
Pathways		Glycogen breakdown (glycogenolysis)	Glycogen breakdown (glycogenolysis) Glycogen breakdown (glycogenolysis)
Drugs			Fostamatinib
Diseases		Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS			Multiple sclerosis ( 31604244) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259)
Interacting Genes		5 interacting genes: DAPK1 MAGEA2 MAGEA2B PHKA2 PHKG1	4 interacting genes: CALM1 CTRC MAPT PHKG2
Entrez ID		5261	5260
HPRD ID		01405	01404
Ensembl ID		ENSG00000156873	ENSG00000164776
Uniprot IDs		P15735	A0A024RDL4 B7Z6U2 Q16816
PDB IDs		2Y7J
Enriched GO Terms of Interacting Partners?
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