PHKG1 and PHKG2

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		PHKG1	PHKG2
Description		phosphorylase kinase catalytic subunit gamma 1	phosphorylase kinase catalytic subunit gamma 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Phosphorylase Kinase Complex	Cytosol Phosphorylase Kinase Complex
	Molecular Function	Phosphorylase Kinase Activity Calmodulin Binding ATP Binding Enzyme Binding Tau-protein Kinase Activity Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Serine/threonine Kinase Activity Phosphorylase Kinase Activity Protein Binding Calmodulin Binding ATP Binding Tau-protein Kinase Activity
	Biological Process	Carbohydrate Metabolic Process Glycogen Biosynthetic Process Glycogen Catabolic Process Protein Phosphorylation	Glycogen Metabolic Process Glycogen Biosynthetic Process Glycogen Catabolic Process Generation Of Precursor Metabolites And Energy Protein Phosphorylation Positive Regulation Of Glycogen Catabolic Process
Pathways		Glycogen breakdown (glycogenolysis) Glycogen breakdown (glycogenolysis)	Glycogen breakdown (glycogenolysis)
Drugs		Fostamatinib
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		Multiple sclerosis ( 31604244) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259)
Interacting Genes		4 interacting genes: CALM1 CTRC MAPT PHKG2	5 interacting genes: DAPK1 MAGEA2 MAGEA2B PHKA2 PHKG1
Entrez ID		5260	5261
HPRD ID		01404	01405
Ensembl ID		ENSG00000164776	ENSG00000156873
Uniprot IDs		A0A024RDL4 B7Z6U2 Q16816	P15735
PDB IDs			2Y7J
Enriched GO Terms of Interacting Partners?
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