ABCB1 and MAPKAP1

Data Source:
BioGRID (two hybrid)

		ABCB1	MAPKAP1
Description		ATP binding cassette subfamily B member 1	MAPK associated protein 1
Image
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Apical Plasma Membrane Extracellular Exosome External Side Of Apical Plasma Membrane	Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Cytoplasmic Vesicle TORC2 Complex
	Molecular Function	Protein Binding ATP Binding ABC-type Xenobiotic Transporter Activity Efflux Transmembrane Transporter Activity ATPase Activity Transmembrane Transporter Activity Ubiquitin Protein Ligase Binding ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity Carboxylic Acid Transmembrane Transporter Activity Phosphatidylcholine Floppase Activity Phosphatidylethanolamine Flippase Activity Ceramide Floppase Activity Floppase Activity	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Protein Kinase Binding Small GTPase Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidic Acid Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Response To Drug Phospholipid Translocation Terpenoid Transport Regulation Of Response To Osmotic Stress Transmembrane Transport Transepithelial Transport Stem Cell Proliferation Ceramide Translocation Export Across Plasma Membrane Transport Across Blood-brain Barrier Positive Regulation Of Anion Channel Activity Carboxylic Acid Transmembrane Transport Xenobiotic Transport Across Blood-brain Barrier Regulation Of Chloride Transport	Substantia Nigra Development Establishment Or Maintenance Of Actin Cytoskeleton Polarity Activation Of Protein Kinase B Activity Positive Regulation Of Peptidyl-serine Phosphorylation TORC2 Signaling Negative Regulation Of Ras Protein Signal Transduction Regulation Of Cellular Response To Oxidative Stress
Pathways		Abacavir transmembrane transport ABC-family proteins mediated transport	PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation
Drugs		ATP Medroxyprogesterone acetate Roxithromycin Fentanyl Voacamine Elacridar Tesmilifene FM-VP4 Zosuquidar Tariquidar Miltefosine Tocofersolan Hycanthone Concanamycin A Dexverapamil Emopamil Lomerizine Tetrandrine Dofequidar Dexniguldipine ONT-093 HM-30181 Desmethylsertraline Reversin 121
Diseases
GWAS		Bone mineral density (spine) and age at menarche ( 26312577) Gallbladder cancer ( 28274756) Neurological blood protein biomarker levels ( 31320639)	Body mass index ( 28892062) Diverticular disease ( 30177863) Fish- and plant-related diet ( 32066663) Gut microbiota relative abundance (Ruminococcus belonging to family Lachnospiraceae) ( 33208821) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Medication use (calcium channel blockers) ( 31015401) Raw vegetable consumption ( 32066663) Resting heart rate ( 27798624) Sleep duration ( 30531941) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		11 interacting genes: BCCIP CAV1 CD4 HAX1 LNX1 MAPKAP1 MAPRE1 NEDD4 PIM1 PSMB8 RNF2	9 interacting genes: ABCB1 AKT1 CDC42EP1 ECI1 MAPK8 NRAS PRKCA SGK1 YWHAG
Entrez ID		5243	79109
HPRD ID		01370	17464
Ensembl ID		ENSG00000085563	ENSG00000119487
Uniprot IDs		A4D1D2 P08183	A0A024R863 Q9BPZ7
PDB IDs		6C0V 6FN1 6FN4 6QEX 7A65 7A69 7A6C 7A6E 7A6F	3VOQ 5ZCS
Enriched GO Terms of Interacting Partners?
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