MAPKAP1 and ECI1

Data Source:
BioGRID (two hybrid)

		MAPKAP1	ECI1
Description		MAPK associated protein 1	enoyl-CoA delta isomerase 1
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Cytoplasmic Vesicle TORC2 Complex	Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Protein Kinase Binding Small GTPase Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidic Acid Binding Phosphatidylinositol-3,5-bisphosphate Binding	Dodecenoyl-CoA Delta-isomerase Activity Enoyl-CoA Hydratase Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds
	Biological Process	Substantia Nigra Development Establishment Or Maintenance Of Actin Cytoskeleton Polarity Activation Of Protein Kinase B Activity Positive Regulation Of Peptidyl-serine Phosphorylation TORC2 Signaling Negative Regulation Of Ras Protein Signal Transduction Regulation Of Cellular Response To Oxidative Stress	Fatty Acid Beta-oxidation
Pathways		PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation	mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
Drugs			Octanoyl-Coenzyme A Benzamidine
Diseases
GWAS		Body mass index ( 28892062) Diverticular disease ( 30177863) Fish- and plant-related diet ( 32066663) Gut microbiota relative abundance (Ruminococcus belonging to family Lachnospiraceae) ( 33208821) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Medication use (calcium channel blockers) ( 31015401) Raw vegetable consumption ( 32066663) Resting heart rate ( 27798624) Sleep duration ( 30531941) Smoking status (ever vs never smokers) ( 30643258)	Anthropometric traits (multi-trait analysis) ( 30166351)
Interacting Genes		9 interacting genes: ABCB1 AKT1 CDC42EP1 ECI1 MAPK8 NRAS PRKCA SGK1 YWHAG	3 interacting genes: APP MAPKAP1 POT1
Entrez ID		79109	1632
HPRD ID		17464	02628
Ensembl ID		ENSG00000119487	ENSG00000167969
Uniprot IDs		A0A024R863 Q9BPZ7	A0A384NKJ3 P42126
PDB IDs		3VOQ 5ZCS	1SG4
Enriched GO Terms of Interacting Partners?
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