PGK1 and HSPH1

Data Source:
HPRD (in vitro)

		PGK1	HSPH1
Description		phosphoglycerate kinase 1	heat shock protein family H (Hsp110) member 1
Image
GO Annotations	Cellular Component	Extracellular Space Cytosol Membrane Membrane Raft Extracellular Exosome	Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Protein-containing Complex Extracellular Exosome Endocytic Vesicle Lumen
	Molecular Function	Phosphoglycerate Kinase Activity Protein Binding ATP Binding ADP Binding Protein-disulfide Reductase Activity	Adenyl-nucleotide Exchange Factor Activity Protein Binding ATP Binding Alpha-tubulin Binding
	Biological Process	Gluconeogenesis Glycolytic Process Phosphorylation Negative Regulation Of Angiogenesis Epithelial Cell Differentiation Plasminogen Activation Canonical Glycolysis Cellular Response To Hypoxia	Receptor-mediated Endocytosis Response To Unfolded Protein Positive Regulation Of MHC Class I Biosynthetic Process Regulation Of Catalytic Activity Chaperone Cofactor-dependent Protein Refolding Positive Regulation Of NK T Cell Activation Regulation Of Cellular Response To Heat
Pathways		Glycolysis Gluconeogenesis Manipulation of host energy metabolism	Scavenging by Class F Receptors Scavenging by Class F Receptors Regulation of HSF1-mediated heat shock response
Drugs		Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate 3-phospho-D-glyceric acid Copper Artenimol	Phenethyl Isothiocyanate
Diseases		Anemia due to disorders of glycolytic enzymes, including: Hexokinase (HK) deficiency; Phosphoglycerate kinase 1 (PGK1) deficiency; Triose-phosphate isomerase (TPI) deficiency; Glucose phosphate isomerase (GPI) deficiency; Bisphosphoglycerate mutase (BPGM) deficiency
GWAS		Mean platelet volume ( 32888494)	Metabolite levels ( 23823483)
Interacting Genes		14 interacting genes: BECN1 CDC7 CSNK2A1 DISC1 GAPDH HIF1A HSPH1 LINC01554 NAA10 PCNA RHOU SUMO2 SUMO4 YWHAQ	16 interacting genes: ADD1 CFL1 CHD3 CSNK2A1 CSNK2A2 DYNLRB1 HSPA8 NMI PAFAH1B1 PAFAH1B3 PGK1 PTEN STK39 TUBA4A UBA1 VAV2
Entrez ID		5230	10808
HPRD ID		02412	09990
Ensembl ID		ENSG00000102144	ENSG00000120694
Uniprot IDs		P00558 V9HWF4	A0A024RDQ0 A0A024RDS1 A0A0A0MSM0 B4DY72 Q92598
PDB IDs		2WZB 2WZC 2WZD 2X13 2X14 2X15 2XE6 2XE7 2XE8 2Y3I 2YBE 2ZGV 3C39 3C3A 3C3B 3C3C 3ZOZ 4AXX 4O33 5M1R 5M3U 5M6Z 5MXM 5NP8 5O7D	6GFA
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?