HSPH1 and CFL1

Data Source:
HPRD (in vitro)

		HSPH1	CFL1
Description		heat shock protein family H (Hsp110) member 1	cofilin 1
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Protein-containing Complex Extracellular Exosome Endocytic Vesicle Lumen	Extracellular Space Nucleus Cytoplasm Cytosol Focal Adhesion Actin Cytoskeleton Membrane Nuclear Matrix Lamellipodium Lamellipodium Membrane Vesicle Ruffle Membrane Extracellular Exosome
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Protein Binding ATP Binding Alpha-tubulin Binding	Protein Binding Actin Filament Binding
	Biological Process	Receptor-mediated Endocytosis Response To Unfolded Protein Positive Regulation Of MHC Class I Biosynthetic Process Regulation Of Catalytic Activity Chaperone Cofactor-dependent Protein Refolding Positive Regulation Of NK T Cell Activation Regulation Of Cellular Response To Heat	Cytoskeleton Organization Rho Protein Signal Transduction Response To Virus Viral Process Regulation Of Cell Morphogenesis Actin Cytoskeleton Organization Actin Filament Depolymerization Actin Filament Fragmentation Interleukin-12-mediated Signaling Pathway Positive Regulation Of Embryonic Development Negative Regulation Of Apoptotic Process Positive Regulation By Host Of Viral Process Cell Motility Actin Filament Severing Establishment Of Spindle Localization Regulation Of Dendritic Spine Morphogenesis
Pathways		Scavenging by Class F Receptors Scavenging by Class F Receptors Regulation of HSF1-mediated heat shock response	Platelet degranulation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling Sema3A PAK dependent Axon repulsion RHO GTPases Activate ROCKs Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		Phenethyl Isothiocyanate	Dodecyldimethylamine N-oxide Copper Artenimol
Diseases
GWAS		Metabolite levels ( 23823483)	Acne (severe) ( 24927181) Basal cell carcinoma ( 31174203) Breast cancer ( 23535729) DNA methylation (variation) ( 23725790) Keratinocyte cancer (MTAG) ( 31174203) Neutrophil count ( 32888494) Platelet count ( 32888494) Psoriasis ( 28537254) White blood cell count ( 32888494)
Interacting Genes		16 interacting genes: ADD1 CFL1 CHD3 CSNK2A1 CSNK2A2 DYNLRB1 HSPA8 NMI PAFAH1B1 PAFAH1B3 PGK1 PTEN STK39 TUBA4A UBA1 VAV2	43 interacting genes: ACTA1 ACTA2 ACTB ACTC1 ACTG1 APP ATP1A1 ATXN1 CFL2 CLCN5 EGFR ERBB2 ERBB3 ERBB4 ESR1 HSPH1 LIMK1 LIMK2 MAPK6 MAPK8IP2 MYCBP NRK POT1 PSEN1 PTEN RAD21 RPS6KA1 SLC2A4 SRC SSH1 SSH2 SSH3 TAB1 TERF1 TESK1 TESK2 TPI1 TRIM15 UCHL5 WDR1 YWHAG YWHAQ YWHAZ
Entrez ID		10808	1072
HPRD ID		09990	03261
Ensembl ID		ENSG00000120694	ENSG00000172757
Uniprot IDs		A0A024RDQ0 A0A024RDS1 A0A0A0MSM0 B4DY72 Q92598	P23528 V9HWI5
PDB IDs		6GFA	1Q8G 1Q8X 3J0S 4BEX 5HVK 5L6W 6UBY 6UC0 6UC4 6VAO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?