PGAM1 and PKP4

Data Source:
HPRD (two hybrid)

		PGAM1	PKP4
Description		phosphoglycerate mutase 1	plakophilin 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Spindle Pole Cornified Envelope Nucleus Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Junction Adherens Junction Cytoplasmic Side Of Plasma Membrane Cell Junction Desmosome Midbody Cell-cell Contact Zone Perinuclear Region Of Cytoplasm Spindle Midzone Mitotic Spindle
	Molecular Function	Bisphosphoglycerate Mutase Activity Phosphoglycerate Mutase Activity Protein Binding Hydrolase Activity Protein Kinase Binding	Protein Binding Cadherin Binding
	Biological Process	Gluconeogenesis Glycolytic Process Regulation Of Glycolytic Process Neutrophil Degranulation Regulation Of Pentose-phosphate Shunt Respiratory Burst Canonical Glycolysis	Cell-cell Junction Assembly Cell-cell Signaling Regulation Of Cell Adhesion Keratinization Positive Regulation Of Cytokinesis Positive Regulation Of GTPase Activity Cornification Cell-cell Adhesion
Pathways		Neutrophil degranulation Glycolysis Gluconeogenesis	Keratinization Formation of the cornified envelope
Drugs		Copper Artenimol
Diseases
GWAS			Borderline personality disorder ( 28632202) Obesity-related traits ( 23251661) Restless legs syndrome ( 29029846)
Interacting Genes		7 interacting genes: ARL4D DCTN1 ERBB2 PCNA PKP4 UNC5CL XRCC6	19 interacting genes: ATPAF2 CDH1 CDH2 CDH5 DSC3 DSP ERBIN GABARAP GOLGA2 LNX1 LZTS2 MINK1 OSGEP PAXIP1 PDZD2 PGAM1 PSEN1 TRIM23 UBASH3B
Entrez ID		5223	8502
HPRD ID		01392	05043
Ensembl ID		ENSG00000171314	ENSG00000144283
Uniprot IDs		B7Z9E5 P18669 Q6FHU2	Q99569
PDB IDs		1LJD 1YFK 1YJX 4GPI 4GPZ 5Y2I 5Y2U 5Y35 5Y64 5Y65 5ZRM 5ZS8 6ISN
Enriched GO Terms of Interacting Partners?
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