PER1 and RIPOR2

Data Source:
BioGRID (two hybrid)

		PER1	RIPOR2
Description		period circadian regulator 1	RHO family interacting cell polarization regulator 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Cytoplasm Cytoskeleton Apical Plasma Membrane Filopodium Stereocilium Stereocilium Membrane
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Corepressor Binding Protein Binding Kinase Binding Chromatin DNA Binding Ubiquitin Protein Ligase Binding E-box Binding	Protein Binding Identical Protein Binding 14-3-3 Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Sodium Ion Transport Circadian Rhythm Entrainment Of Circadian Clock Posttranscriptional Regulation Of Gene Expression Circadian Regulation Of Gene Expression Regulation Of Hair Cycle Regulation Of Circadian Rhythm Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Entrainment Of Circadian Clock By Photoperiod Histone H3 Acetylation Histone H4 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of JNK Cascade Response To CAMP Histone H3 Deacetylation Circadian Regulation Of Translation Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of P38MAPK Cascade Negative Regulation Of Glucocorticoid Receptor Signaling Pathway	Chemotaxis Cell Adhesion Negative Regulation Of Cell Adhesion Sensory Perception Of Sound Negative Regulation Of Rho Protein Signal Transduction Establishment Of Protein Localization Positive Regulation Of Myoblast Differentiation Skeletal Muscle Fiber Development Protein Homooligomerization Positive Regulation Of Filopodium Assembly Auditory Receptor Cell Stereocilium Organization Cellular Response To Mechanical Stimulus Positive Regulation Of Neutrophil Chemotaxis Positive Regulation Of Myoblast Fusion Negative Regulation Of Establishment Of T Cell Polarity Negative Regulation Of Protein Localization To Cell Leading Edge Cellular Response To Chemokine Regulation Of Establishment Of Cell Polarity Positive Regulation Of Neutrophil Extravasation Negative Regulation Of T Cell Migration Negative Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity
Pathways		Circadian Clock
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) High light scatter reticulocyte percentage of red cells ( 32888494)
Interacting Genes		19 interacting genes: CCDC57 CRY1 CRY2 CSNK1D CSNK1E CSNK1G2 CSNK2B DELEC1 GPRASP1 HIF1A LTB4R2 PER2 PER3 PNMA1 RBPMS RIPOR2 TIMELESS TNS2 TRIP6	6 interacting genes: MAP2K2 MTNR1B PER1 RHOA RHOC YWHAG
Entrez ID		5187	9750
HPRD ID		03774	12881
Ensembl ID		ENSG00000179094	ENSG00000111913
Uniprot IDs		O15534	A0A024QZY9 A0A024R028 A0A2R8Y7B3 A0A2R8YEE0 B7Z5J9 B7Z6D6 B7Z6U4 F5GX51 F5H029 Q9Y4F9
PDB IDs		1UL6
Enriched GO Terms of Interacting Partners?
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