MAP3K20 and ZNF35

Data Source:
BioGRID (two hybrid)

		MAP3K20	ZNF35
Description		mitogen-activated protein kinase kinase kinase 20	zinc finger protein 35
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Perinuclear Region Of Cytoplasm
	Molecular Function	Magnesium Ion Binding RNA Binding Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	DNA Damage Checkpoint Activation Of MAPKK Activity Protein Phosphorylation Cytoskeleton Organization Cell Cycle Arrest Activation Of JUN Kinase Activity Cell Death Cell Differentiation Embryonic Digit Morphogenesis Positive Regulation Of Apoptotic Process Stress-activated MAPK Cascade Limb Development Cellular Response To Gamma Radiation Positive Regulation Of Mitotic DNA Damage Checkpoint	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Spermatogenesis Cellular Response To Retinoic Acid
Pathways
Drugs		Dasatinib Fostamatinib
Diseases
GWAS			Bipolar disorder ( 31043756)
Interacting Genes		32 interacting genes: CCDC69 CRMP1 DDAH2 EZH2 IGHM ITSN1 MAP2K4 MAP2K6 MAP2K7 MIDN MPP1 NEDD4L RBX1 RNF19A RPS6KA5 SMARCB1 SRPK2 TGFBR1 UNC119 VPS33B YWHAG YWHAZ ZFP1 ZFP2 ZNF33A ZNF35 ZNF567 ZNF593 ZNF660 ZNF71 ZNF746 ZNF775	33 interacting genes: APP ATPAF2 CCDC130 CCDC136 CDC5L CDR2 CDR2L CEP70 CREB1 CWF19L2 EEF2KMT EXOC8 FSD2 GEMIN4 GOLGA2 GOLGA6L9 GRIPAP1 HOMER3 HOMEZ HOOK1 HOOK2 LZTS1 MAP3K20 MCC MTUS2 MYD88 NDEL1 PIBF1 PICK1 PNMA1 PRKAR1B TRAF2 ZBTB8A
Entrez ID		51776	7584
HPRD ID		11791	01920
Ensembl ID		ENSG00000091436	ENSG00000169981
Uniprot IDs		D4Q8H0 Q9NYL2	P13682
PDB IDs		5HES 5X5O 6JUT 6JUU
Enriched GO Terms of Interacting Partners?
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