RSF1 and SMARCA5

Data Source:
HPRD (in vivo)

		RSF1	SMARCA5
Description		remodeling and spacing factor 1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm RSF Complex	Condensed Chromosome Fibrillar Center Nucleus Nucleoplasm Chromatin Silencing Complex Cytosol NURF Complex RSF Complex Intracellular Membrane-bounded Organelle Nuclear Replication Fork
	Molecular Function	Transcription Coregulator Activity Protein Binding ATPase Activity Histone Binding Metal Ion Binding	DNA Binding Helicase Activity Protein Binding ATP Binding DNA-dependent ATPase Activity ATPase Activity Nucleosome Binding Histone Binding
	Biological Process	Nucleosome Assembly Chromatin Remodeling DNA-templated Transcription, Initiation Nucleosome Positioning CENP-A Containing Nucleosome Assembly Negative Regulation Of DNA Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Viral Transcription	RDNA Heterochromatin Assembly Nucleosome Assembly Chromatin Remodeling DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Nucleosome Positioning CENP-A Containing Nucleosome Assembly ATP-dependent Chromatin Remodeling Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Leukemia Inhibitory Factor
Pathways		Deposition of new CENPA-containing nucleosomes at the centromere	NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Deposition of new CENPA-containing nucleosomes at the centromere
Drugs			Beta-D-Glucose 4-Deoxy-Alpha-D-Glucose
Diseases
GWAS		Left-handedness ( 32989287) Tourette syndrome ( 30818990)	Height ( 31562340) Malaria ( 31844061)
Interacting Genes		3 interacting genes: CSNK2A1 NFKB1 SMARCA5	18 interacting genes: BAZ1A BAZ1B BAZ2A CDT1 CHRAC1 CREB1 CTNNB1 DNMT3B H3-3A H3C1 H4-16 HDAC2 MAF POLE3 PTEN RAD21 RSF1 SATB1
Entrez ID		51773	8467
HPRD ID		10537	04538
Ensembl ID		ENSG00000048649	ENSG00000153147
Uniprot IDs		Q05DG0 Q96T23	O60264
PDB IDs			6NE3
Enriched GO Terms of Interacting Partners?
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