GNG13 and WASHC3

Data Source:
BioGRID (two hybrid)

		GNG13	WASHC3
Description		G protein subunit gamma 13	WASH complex subunit 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Heterotrimeric G-protein Complex Plasma Membrane Dendrite	Early Endosome WASH Complex
	Molecular Function	Protein Binding G-protein Beta-subunit Binding	Protein Binding
	Biological Process	Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Sensory Perception Of Taste	Exocytosis Biological_process Protein Transport Actin Filament Polymerization
Pathways		Activation of G protein gated Potassium channels Glucagon signaling in metabolic regulation G-protein activation Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) ADP signalling through P2Y purinoceptor 12 G beta:gamma signalling through PI3Kgamma Prostacyclin signalling through prostacyclin receptor Prostacyclin signalling through prostacyclin receptor Adrenaline,noradrenaline inhibits insulin secretion Adrenaline,noradrenaline inhibits insulin secretion Ca2+ pathway Ca2+ pathway G alpha (q) signalling events G alpha (12/13) signalling events G beta:gamma signalling through PLC beta G alpha (s) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 G alpha (i) signalling events G alpha (z) signalling events Glucagon-type ligand receptors Thromboxane signalling through TP receptor Vasopressin regulates renal water homeostasis via Aquaporins Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding G beta:gamma signalling through BTK G beta:gamma signalling through CDC42 Extra-nuclear estrogen signaling ADORA2B mediated anti-inflammatory cytokines production Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Metabolite levels ( 23823483)
Interacting Genes		39 interacting genes: ABI3 ADAMTSL4 BEX5 CCHCR1 CTAG1A CTAG1B CYSRT1 DISC1 DLG1 DLG4 EMILIN1 FTO GLRX3 GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 HAUS3 HOXA10 KRT27 KRT34 KRT37 KRT38 KRTAP9-2 LIN7B MEOX2 PAX5 PLSCR2 RASSF10 RPRM RSPO4 TEAD2 TEPSIN TRIM54 UQCC2 VPS16 WASHC3	56 interacting genes: ABI2 BFSP2 BLOC1S2 BLOC1S6 C20orf202 CCDC197 CCHCR1 CENPK CEP55 CKAP4 COG6 DTNBP1 GDF9 GNG13 GOLGA2 HAUS1 HSBP1 HSPB1 IFT20 IKBIP INSYN1 KDM1A KNSTRN KRT27 KRT6A KRT71 KRT75 LAMC1 LHX4 LMNB2 LUC7L2 MCRS1 MOB1A MOB1B MYOZ1 NDC80 NUP62 OPTN PAX6 PBXIP1 PCM1 PHOSPHO2 PTN RABEP1 SCARA5 SDCBP SNAP25 SNAPIN SRGAP2B SYCE1 TEX35 TFIP11 TXLNA TXLNB VPS52 WASHC1
Entrez ID		51764	51019
HPRD ID		12116	13031
Ensembl ID		ENSG00000127588	ENSG00000120860
Uniprot IDs		Q9P2W3	F5GWI9 F5GZ97 Q9Y3C0
PDB IDs
Enriched GO Terms of Interacting Partners?
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