WASHC3 and PCM1

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		WASHC3	PCM1
Description		WASH complex subunit 3	pericentriolar material 1
Image		No pdb structure
GO Annotations	Cellular Component	Early Endosome WASH Complex	Pericentriolar Material Cytoplasm Centrosome Centriole Cytosol Membrane Nuclear Membrane Protein-containing Complex Centriolar Satellite Ciliary Transition Zone Ciliary Basal Body Apical Part Of Cell Non-motile Cilium
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Exocytosis Biological_process Protein Transport Actin Filament Polymerization	G2/M Transition Of Mitotic Cell Cycle Neuron Migration Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Interkinetic Nuclear Migration Cytoplasmic Microtubule Organization Microtubule Anchoring Microtubule Anchoring At Centrosome Social Behavior Intraciliary Transport Involved In Cilium Assembly Negative Regulation Of Neurogenesis Cilium Assembly Protein Localization To Centrosome Positive Regulation Of Intracellular Protein Transport Neuronal Stem Cell Population Maintenance Ciliary Basal Body-plasma Membrane Docking Non-motile Cilium Assembly
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS			Atrial fibrillation ( 28416818) Economic and political preferences ( 22566634) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Triglyceride levels ( 32203549) Waist-hip ratio ( 30108283) Weight ( 28552196)
Interacting Genes		56 interacting genes: ABI2 BFSP2 BLOC1S2 BLOC1S6 C20orf202 CCDC197 CCHCR1 CENPK CEP55 CKAP4 COG6 DTNBP1 GDF9 GNG13 GOLGA2 HAUS1 HSBP1 HSPB1 IFT20 IKBIP INSYN1 KDM1A KNSTRN KRT27 KRT6A KRT71 KRT75 LAMC1 LHX4 LMNB2 LUC7L2 MCRS1 MOB1A MOB1B MYOZ1 NDC80 NUP62 OPTN PAX6 PBXIP1 PCM1 PHOSPHO2 PTN RABEP1 SCARA5 SDCBP SNAP25 SNAPIN SRGAP2B SYCE1 TEX35 TFIP11 TXLNA TXLNB VPS52 WASHC1	43 interacting genes: ABI1 ABI2 AKAP9 BBS4 CASK CCDC172 CCHCR1 CDC42 CEP72 CYTH4 DDIT3 DDX23 DYNLL1 E2F4 ECPAS EPS8 EXOC8 FAM81A FXR2 GABARAP GOLGA2 HAP1 ING5 KLC1 KLC4 KRT15 KRT19 KRT24 MCRS1 NDC80 NECAB2 PCNT PRC1 PRKCI RALBP1 RBM5 RINT1 RPA2 TFIP11 TTC8 WASHC3 YWHAE YWHAQ
Entrez ID		51019	5108
HPRD ID		13031	02624
Ensembl ID		ENSG00000120860	ENSG00000078674
Uniprot IDs		F5GWI9 F5GZ97 Q9Y3C0	A2RUU9 B9EIS5 Q15154
PDB IDs			6HYL 6HYM
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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