GPRC5B and TMEM120A

Data Source:
BioGRID (two hybrid)

		GPRC5B	TMEM120A
Description		G protein-coupled receptor class C group 5 member B	transmembrane protein 120A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Nucleolus Cytosol Plasma Membrane Cell Surface Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle Receptor Complex Extracellular Exosome	Cellular_component Nuclear Inner Membrane Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Binding G Protein-coupled Receptor Activity Protein Kinase Binding Protein Kinase Activator Activity	Molecular_function Ion Channel Activity Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Activation Of Protein Kinase Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Neuron Differentiation Positive Regulation Of Inflammatory Response Positive Regulation Of Macrophage Cytokine Production Positive Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Canonical Wnt Signaling Pathway	Ion Transmembrane Transport Fat Cell Differentiation Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Protein Homooligomerization Protein Heterooligomerization
Pathways
Drugs
Diseases
GWAS		Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Birth weight ( 31043758) Body mass index ( 26961502 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Childhood body mass index ( 33045005) Hip circumference ( 25673412) L-selectin levels ( 25576479) Menarche (age at onset) ( 25231870) Obesity ( 23563607) Obesity-related traits ( 23251661) Waist circumference ( 25673412)	Coffee consumption ( 25288136) Coffee consumption (cups per day) ( 25288136)
Interacting Genes		5 interacting genes: ADRB2 C11orf71 FUCA2 HTR2C TMEM120A	24 interacting genes: AQP6 CYBRD1 FAM209A FBXO7 GOT1 GPRC5B HSD17B13 LEPROT LRRC25 ORMDL2 PAXIP1 PPP1CC PTAFR SCN3B STX1A STX2 TMEM14B TMEM35A TMEM86B TMX2 TPRG1 TSPAN18 UBC VKORC1
Entrez ID		51704	83862
HPRD ID		16177	15543
Ensembl ID		ENSG00000167191	ENSG00000189077
Uniprot IDs		A0A024QYX2 B7Z831 Q9NZH0	A0A087X266 Q9BXJ8
PDB IDs
Enriched GO Terms of Interacting Partners?
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