VPS29 and FRA10AC1

		VPS29	FRA10AC1
Description		VPS29 retromer complex component	FRA10A associated CGG repeat 1
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Late Endosome Cytosol Endosome Membrane Retromer Complex Retromer, Cargo-selective Complex Intracellular Membrane-bounded Organelle	Nucleus
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding Phosphatase Activity
	Biological Process	Intracellular Protein Transport Regulation Of Autophagy Viral Process Wnt Signaling Pathway Endocytic Recycling Retrograde Transport, Endosome To Golgi Retrograde Transport, Endosome To Plasma Membrane	Dephosphorylation
Pathways		WNT ligand biogenesis and trafficking
Drugs
Diseases
GWAS			Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid AB1-42 levels ( 26252872 29274321) Refractive error ( 32231278)
Interacting Genes		6 interacting genes: APP FRA10AC1 RAB7A RGS2 TMCO4 VPS35	28 interacting genes: ADPRS C7orf25 CHERP CWC27 EEF1D ESS2 GATD3A GDPD2 GLRX3 HABP4 IK KASH5 MAP3K12 MFAP1 MOB2 NKAP PLPPR4 PRPF3 PRPF40A SAP30BP SF3B2 THOC1 TRIM41 TTC14 U2AF1 VPS29 ZCCHC10 ZNF830
Entrez ID		51699	118924
HPRD ID		09499	12319
Ensembl ID		ENSG00000111237	ENSG00000148690
Uniprot IDs		A0A384MR19 F8VXU5 Q9UBQ0	Q70Z53
PDB IDs		1W24 2R17 5GTU 5OSH 5OSI 5WYH
Enriched GO Terms of Interacting Partners?
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