FRA10AC1 and THOC1

Data Source:
BioGRID (two hybrid)

		FRA10AC1	THOC1
Description		FRA10A associated CGG repeat 1	THO complex 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck
	Molecular Function	Protein Binding Phosphatase Activity	DNA Binding RNA Binding Protein Binding
	Biological Process	Dephosphorylation	Regulation Of DNA Recombination RNA Processing RNA Export From Nucleus MRNA Export From Nucleus Apoptotic Process Signal Transduction RNA Splicing MRNA 3'-end Processing Replication Fork Processing Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Viral MRNA Export From Host Cell Nucleus Negative Regulation Of Isotype Switching To IgA Isotypes Negative Regulation Of DNA Damage Checkpoint
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid AB1-42 levels ( 26252872 29274321) Refractive error ( 32231278)	Bipolar disorder ( 20351715) Bipolar disorder or major depressive disorder ( 20351715) Height ( 31562340) Menarche (age at onset) ( 29773799) Triglyceride levels ( 32203549)
Interacting Genes		28 interacting genes: ADPRS C7orf25 CHERP CWC27 EEF1D ESS2 GATD3A GDPD2 GLRX3 HABP4 IK KASH5 MAP3K12 MFAP1 MOB2 NKAP PLPPR4 PRPF3 PRPF40A SAP30BP SF3B2 THOC1 TRIM41 TTC14 U2AF1 VPS29 ZCCHC10 ZNF830	26 interacting genes: AGR2 AKAP9 BHLHB9 CTAG1A CTAG1B DHX8 EXOC5 FRA10AC1 IK MAGEB4 MOAP1 MTNR1B NEDD4 PAX6 PPP1R12C RABGEF1 RB1 REL SAP30BP SF3B2 TADA2A TRIM27 TRIM54 USHBP1 WDR77 ZMYND12
Entrez ID		118924	9984
HPRD ID		12319	09498
Ensembl ID		ENSG00000148690	ENSG00000079134
Uniprot IDs		Q70Z53	Q96FV9
PDB IDs			1WXP
Enriched GO Terms of Interacting Partners?
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