TRAPPC2L and TUBB3

Data Source:
BioGRID (affinity chromatography technology)

		TRAPPC2L	TUBB3
Description		trafficking protein particle complex subunit 2L	tubulin beta 3 class III
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Cytoplasm Endoplasmic Reticulum Cytosol TRAPP Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Microtubule Lamellipodium Filopodium Axon Dendrite Growth Cone Extracellular Exosome
	Molecular Function	Protein Binding	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Netrin Receptor Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport COPII Vesicle Coating	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Axon Guidance Netrin-activated Signaling Pathway Dorsal Root Ganglion Development
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins
Drugs			Epothilone D Patupilone Ixabepilone CYT997 ZEN-012 Phenethyl Isothiocyanate
Diseases			Congenital fibrosis of the extraocular muscles (CFEOM)
GWAS		Carotid intima media thickness (mean) ( 31801372) Hair color ( 26926045)	Brain morphology (MOSTest) ( 32665545) Cutaneous malignant melanoma ( 32341527) Cutaneous squamous cell carcinoma ( 32041948) Left-handedness ( 32989287) Liver fibrogenesis (alpha smooth muscle actin levels) ( 32953199) Obsessive-compulsive disorder or autism spectrum disorder ( 28641744) Red vs. brown/black hair color ( 30531825) Rosacea symptom severity ( 29771307) Squamous cell carcinoma ( 31174203)
Interacting Genes		27 interacting genes: APP BLZF1 BSDC1 C11orf68 CEP57L1 GPANK1 LCN2 LHX2 LMO3 MEI4 MEOX1 MEOX2 POLR2G RABEP1 REL REPS1 SSX2 SSX2B TCF4 TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC6A TRAPPC6B TRIP6 YPEL3 ZBTB42	34 interacting genes: ABCC2 ANXA7 ARHGEF7 CAMSAP3 CDC42 CDKN1A DDX39B DUX4 EEF1G GABARAP GZMK HEXD INSM1 KHDRBS1 LAPTM4A LIG1 LINC01554 MAP7D3 MAPT MRPL28 MTCL1 MTDH PHIP PLK1 RCC1 RILPL2 ROBO1 SEL1L3 SMN1 SPTSSA TERF1 TF TK1 TPTE
Entrez ID		51693	10381
HPRD ID		13711	04044
Ensembl ID		ENSG00000167515	ENSG00000258947
Uniprot IDs		A0A0B4J294 H3BQQ8 H3BUK6 Q9UL33	Q13509 Q53G92
PDB IDs			5IJ0 5IJ9 5JCO 6E7B 6S8L 6WSL
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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