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TUBB3 and INSM1
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
TUBB3
INSM1
Description
tubulin beta 3 class III
INSM transcriptional repressor 1
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Microtubule
Lamellipodium
Filopodium
Axon
Dendrite
Growth Cone
Extracellular Exosome
Nucleus
Nucleoplasm
Transcription Repressor Complex
Molecular Function
GTPase Activity
Structural Constituent Of Cytoskeleton
Protein Binding
GTP Binding
Netrin Receptor Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Cyclin Binding
Chromatin DNA Binding
Histone Deacetylase Binding
Metal Ion Binding
Biological Process
Microtubule Cytoskeleton Organization
Mitotic Cell Cycle
Axon Guidance
Netrin-activated Signaling Pathway
Dorsal Root Ganglion Development
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Protein Phosphorylation
Type B Pancreatic Cell Differentiation
Pancreatic A Cell Differentiation
Type B Pancreatic Cell Development
Noradrenergic Neuron Development
Cell Cycle
Negative Regulation Of Cell Population Proliferation
Regulation Of Gene Expression
Regulation Of Cell Cycle Process
Neuron Differentiation
Positive Regulation Of Cell Migration
Endocrine Pancreas Development
Norepinephrine Biosynthetic Process
Regulation Of Protein-containing Complex Assembly
Positive Regulation Of Cell Differentiation
Transdifferentiation
Adrenal Chromaffin Cell Differentiation
Sympathetic Ganglion Development
Positive Regulation Of Cell Cycle Arrest
Positive Regulation Of Neural Precursor Cell Proliferation
Pathways
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Gap junction assembly
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Recruitment of NuMA to mitotic centrosomes
Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC
Post-chaperonin tubulin folding pathway
Recycling pathway of L1
Recycling pathway of L1
Hedgehog 'off' state
Cilium Assembly
Intraflagellar transport
RHO GTPases activate IQGAPs
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
Carboxyterminal post-translational modifications of tubulin
Carboxyterminal post-translational modifications of tubulin
HCMV Early Events
Assembly and cell surface presentation of NMDA receptors
Activation of AMPK downstream of NMDARs
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Sealing of the nuclear envelope (NE) by ESCRT-III
Kinesins
Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells
Drugs
Epothilone D
Patupilone
Ixabepilone
CYT997
ZEN-012
Phenethyl Isothiocyanate
Diseases
Congenital fibrosis of the extraocular muscles (CFEOM)
GWAS
Brain morphology (MOSTest) (
32665545
)
Cutaneous malignant melanoma (
32341527
)
Cutaneous squamous cell carcinoma (
32041948
)
Left-handedness (
32989287
)
Liver fibrogenesis (alpha smooth muscle actin levels) (
32953199
)
Obsessive-compulsive disorder or autism spectrum disorder (
28641744
)
Red vs. brown/black hair color (
30531825
)
Rosacea symptom severity (
29771307
)
Squamous cell carcinoma (
31174203
)
Interacting Genes
34 interacting genes:
ABCC2
ANXA7
ARHGEF7
CAMSAP3
CDC42
CDKN1A
DDX39B
DUX4
EEF1G
GABARAP
GZMK
HEXD
INSM1
KHDRBS1
LAPTM4A
LIG1
LINC01554
MAP7D3
MAPT
MRPL28
MTCL1
MTDH
PHIP
PLK1
RCC1
RILPL2
ROBO1
SEL1L3
SMN1
SPTSSA
TERF1
TF
TK1
TPTE
5 interacting genes:
CCND1
KDM1A
MPP3
SORBS1
TUBB3
Entrez ID
10381
3642
HPRD ID
04044
02480
Ensembl ID
ENSG00000258947
ENSG00000173404
Uniprot IDs
Q13509
Q53G92
Q01101
PDB IDs
5IJ0
5IJ9
5JCO
6E7B
6S8L
6WSL
2LV2
3ZMS
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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