DYNC2LI1 and ITGB1BP1

Data Source:
BioGRID (affinity chromatography technology)

		DYNC2LI1	ITGB1BP1
Description		dynein cytoplasmic 2 light intermediate chain 1	integrin subunit beta 1 binding protein 1
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Centrosome Cytoplasmic Dynein Complex Cytoplasmic Microtubule Cilium Axoneme Intraciliary Transport Particle Motile Cilium Ciliary Transition Zone Ciliary Basal Body Apical Part Of Cell Ciliary Tip	Ruffle Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Membrane Nuclear Body Lamellipodium Centriolar Satellite Perinuclear Region Of Cytoplasm Cell Periphery
	Molecular Function	Motor Activity Protein Binding Dynein Heavy Chain Binding	GDP-dissociation Inhibitor Activity Integrin Binding Protein Binding
	Biological Process	Determination Of Left/right Symmetry Intraciliary Retrograde Transport Intraciliary Transport Involved In Cilium Assembly Regulation Of Cilium Assembly	Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Negative Regulation Of Protein Kinase Activity Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Cell-matrix Adhesion Notch Signaling Pathway Integrin-mediated Signaling Pathway Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Fibroblast Migration Cell Migration Cell Differentiation Biomineral Tissue Development Negative Regulation Of Protein Binding Activation Of Protein Kinase B Activity Integrin Activation Regulation Of Cell Adhesion Mediated By Integrin Tube Formation Intracellular Signal Transduction Cellular Response To Vascular Endothelial Growth Factor Stimulus Regulation Of GTPase Activity Receptor Clustering Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Notch Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Myoblast Migration Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Cell Division Negative Regulation Of Focal Adhesion Assembly Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of ERK1 And ERK2 Cascade Protein Localization To Plasma Membrane Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Protein Targeting To Membrane Negative Regulation Of Protein Targeting To Membrane Blood Vessel Diameter Maintenance Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Integrin-mediated Signaling Pathway
Pathways		Intraflagellar transport
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Hematocrit ( 32888494) Hemoglobin ( 32888494) Red blood cell count ( 32888494) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		2 interacting genes: DCDC2 DYNC2H1	19 interacting genes: APP CAMK2A CCDC33 DLD EEF1A1 FAF1 FIGNL1 GSDME ITGB1 KRIT1 LRP1 LRP2 LRP8 RHOH SLC35F5 SMO SMURF1 SMURF2 UTRN
Entrez ID		51626	9270
HPRD ID		13116	06194
Ensembl ID		ENSG00000138036	ENSG00000119185
Uniprot IDs		Q8TCX1	B4DQY5 O14713
PDB IDs		6RLB 6SC2	1K11 4DX8 4DX9 4JIF
Enriched GO Terms of Interacting Partners?
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