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ERGIC3 and ZDHHC15
Data Source:
BioGRID
(two hybrid)
ERGIC3
ZDHHC15
Description
ERGIC and golgi 3
zinc finger DHHC-type palmitoyltransferase 15
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Membrane
COPII-coated ER To Golgi Transport Vesicle
Integral Component Of Golgi Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Golgi Membrane
Endoplasmic Reticulum
Golgi Apparatus
Postsynaptic Density
Integral Component Of Golgi Membrane
Postsynapse
Molecular Function
Protein Binding
Protein Binding
Zinc Ion Binding
Palmitoyltransferase Activity
Protein-cysteine S-palmitoyltransferase Activity
Biological Process
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum
Protein Targeting To Membrane
Synaptic Vesicle Maturation
Protein Phosphopantetheinylation
Peptidyl-L-cysteine S-palmitoylation
Protein Palmitoylation
Regulation Of Dendritic Spine Morphogenesis
Protein Localization To Postsynapse
Protein Localization To Membrane
Protein Targeting To Golgi Apparatus
Positive Regulation Of Dendrite Development
Pathways
Drugs
Diseases
Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS
Apolipoprotein B levels (
32203549
)
Brain morphology (MOSTest) (
32665545
)
Cholesterol, total (
24097068
25961943
20686565
)
Height (
28552196
)
Hip circumference adjusted for BMI (
28552196
)
LDL cholesterol levels (
32203549
)
Refractive error (
32231278
)
Schizophrenia (
28991256
)
Total cholesterol levels (
28334899
30275531
)
Triglycerides (
25961943
)
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI (age >50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
205 interacting genes:
ABHD16A
AGPAT4
AGTRAP
AIG1
ALG10
AOC2
APOC3
APOD
AQP10
AQP2
AQP3
ASGR1
BCL2L1
BET1
BIK
BNIP3
BTN2A2
BUD31
C14orf180
C2
C3orf52
C4orf3
CCDC167
CCR2
CCR4
CCR8
CD207
CD302
CD81
CDIPT
CDS2
CFHR5
CHRM4
CIAO2A
CLCA4
CLDN19
CLDN8
CLDND2
CMTM5
CNIH1
CNIH3
COL4A5
COX20
CTSA
CTXN3
CXorf66
CYB561
CYB561D2
CYBC1
CYP4F2
DEFB103A
DEFB103B
EBP
EMC6
EMP1
EMP3
ENTPD3
ERGIC1
EXTL1
F2RL1
FA2H
FAM3C
FAXDC2
FETUB
FIS1
FKBP8
FXYD2
FXYD3
FXYD6
GAST
GIMAP1
GIMAP5
GJB2
GPM6B
GPR151
GPR35
GPR37
GYPA
HHATL
HMOX1
HMOX2
IFITM3
IGFBP5
ITGAM
JAGN1
KCNK1
LHFPL5
LPAR3
LPCAT2
MARCHF2
MARCHF5
MFF
MFSD6
MIP
MS4A13
MYADM
NDRG4
NDUFB6
NEU1
NINJ2
NKG7
NRG4
NRM
NSG1
ORMDL1
ORMDL3
PAQR5
PAQR7
PEX11G
PEX16
PGAP2
PLLP
PLP1
PLPP4
PMP22
POMGNT1
RFT1
RHAG
RTP2
RUSF1
SCARB2
SCD
SEC22B
SEC23A
SELENOK
SERP2
SFXN5
SLC13A3
SLC1A1
SLC29A2
SLC35A1
SLC35A4
SLC35B2
SLC35B4
SLC38A7
SLC41A1
SLC41A2
SLC49A3
SMAGP
SMCO4
SMIM1
SMIM3
SNORC
SPN
STATH
STX12
STX1B
STX3
STX8
SYNGR1
SYNJ2BP
SYS1
TAP1
TECR
TF
THBD
TM4SF4
TMEM100
TMEM107
TMEM109
TMEM120B
TMEM128
TMEM141
TMEM14A
TMEM14B
TMEM179B
TMEM203
TMEM218
TMEM222
TMEM229B
TMEM243
TMEM42
TMEM60
TMEM65
TMEM86A
TMEM86B
TMEM97
TMUB2
TNFRSF10C
TOMM6
TRAM1L1
TRARG1
TRIM32
TSPAN33
TSPO2
UBE2D3
UBIAD1
UNC50
UNC93B1
VAMP1
VAMP2
VAMP3
VAMP4
VKORC1L1
VMP1
VSTM1
VTI1B
YIF1A
YIPF1
YIPF2
YIPF4
YIPF6
ZDHHC15
ZDHHC21
ZFPL1
48 interacting genes:
ADCYAP1R1
ARL13B
BNIP3
C14orf180
CD79A
CELA2B
CERCAM
CLEC10A
CLRN1
CREB3L1
CYB5R3
DHRSX
ERGIC3
FAM241B
GIMAP1
GOLGA7B
GPR152
LEMD1
LEPROTL1
LHFPL5
LMNA
LSMEM1
MCEMP1
MTIF3
ORMDL1
ORMDL2
PEX16
PLLP
PRAF2
PVR
RUSF1
SLC10A6
SMIM1
SNORC
STX3
TBXA2R
TMEFF2
TMEM120B
TMEM128
TMEM14C
TMEM222
TMEM42
TMEM52B
TNFRSF10B
TSNARE1
TUFM
VAPB
YIPF4
Entrez ID
51614
158866
HPRD ID
15306
06758
Ensembl ID
ENSG00000125991
ENSG00000102383
Uniprot IDs
A2TJK5
Q9Y282
B3KY34
Q96MV8
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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