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ARHGDIB and UFM1
Data Source:
BioGRID
(two hybrid)
ARHGDIB
UFM1
Description
Rho GDP dissociation inhibitor beta
ubiquitin fold modifier 1
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Cytoskeleton
Membrane
Cytoplasmic Vesicle
Extracellular Exosome
Nucleus
Cytoplasm
Endoplasmic Reticulum
Molecular Function
GTPase Activity
Rho GDP-dissociation Inhibitor Activity
GTPase Activator Activity
Protein Binding
Small GTPase Binding
Protein Binding
Biological Process
Negative Regulation Of Cell Adhesion
Rho Protein Signal Transduction
Multicellular Organism Development
Regulation Of Rho Protein Signal Transduction
Positive Regulation Of GTPase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Cellular Response To Redox State
Negative Regulation Of Trophoblast Cell Migration
Regulation Of Actin Cytoskeleton Reorganization
Brain Development
Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Response To Endoplasmic Reticulum Stress
Negative Regulation Of Protein Import Into Nucleus
Negative Regulation Of Apoptotic Process
Reticulophagy
Protein Ufmylation
Protein K69-linked Ufmylation
Pathways
Rho GTPase cycle
Drugs
Diseases
GWAS
Aggressiveness in attention deficit hyperactivity disorder (
27021288
)
Low vWF levels (
26486471
)
Schizophrenia (
30285260
)
Interacting Genes
13 interacting genes:
ANKRD1
APP
CASP3
CDC42
EZR
RAC1
RAC2
RAC3
RHOA
RHOH
UBE3A
UFM1
VAV1
16 interacting genes:
ARHGDIA
ARHGDIB
DIABLO
GSK3B
INCA1
KCTD21
RPS6KA6
TSC22D2
UBA5
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E3
UBE2W
Entrez ID
397
51569
HPRD ID
04162
15644
Ensembl ID
ENSG00000111348
ENSG00000120686
Uniprot IDs
A0A024RAS5
P52566
P61960
PDB IDs
1DS6
5H1D
1WXS
5HKH
5IA7
5IA8
5IAA
5L95
6H77
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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