ARHGDIB and UFM1

Data Source:
BioGRID (two hybrid)

		ARHGDIB	UFM1
Description		Rho GDP dissociation inhibitor beta	ubiquitin fold modifier 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Membrane Cytoplasmic Vesicle Extracellular Exosome	Nucleus Cytoplasm Endoplasmic Reticulum
	Molecular Function	GTPase Activity Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Small GTPase Binding	Protein Binding
	Biological Process	Negative Regulation Of Cell Adhesion Rho Protein Signal Transduction Multicellular Organism Development Regulation Of Rho Protein Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Cellular Response To Redox State Negative Regulation Of Trophoblast Cell Migration Regulation Of Actin Cytoskeleton Reorganization	Brain Development Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Apoptotic Process Reticulophagy Protein Ufmylation Protein K69-linked Ufmylation
Pathways		Rho GTPase cycle
Drugs
Diseases
GWAS			Aggressiveness in attention deficit hyperactivity disorder ( 27021288) Low vWF levels ( 26486471) Schizophrenia ( 30285260)
Interacting Genes		13 interacting genes: ANKRD1 APP CASP3 CDC42 EZR RAC1 RAC2 RAC3 RHOA RHOH UBE3A UFM1 VAV1	16 interacting genes: ARHGDIA ARHGDIB DIABLO GSK3B INCA1 KCTD21 RPS6KA6 TSC22D2 UBA5 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2W
Entrez ID		397	51569
HPRD ID		04162	15644
Ensembl ID		ENSG00000111348	ENSG00000120686
Uniprot IDs		A0A024RAS5 P52566	P61960
PDB IDs		1DS6 5H1D	1WXS 5HKH 5IA7 5IA8 5IAA 5L95 6H77
Enriched GO Terms of Interacting Partners?
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