GSKIP and PEX19

Data Source:
BioGRID (two hybrid)

		GSKIP	PEX19
Description		GSK3B interacting protein	peroxisomal biogenesis factor 19
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Brush Border Membrane Protein-containing Complex
	Molecular Function	Protein Kinase Inhibitor Activity Protein Binding Beta-catenin Binding Kinase Regulator Activity Protein Kinase Binding Protein Kinase A Regulatory Subunit Binding Protein Kinase A Binding	Protein Binding Peroxisome Membrane Targeting Sequence Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Protein N-terminus Binding ATPase Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Regulation Of Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway	Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Fission Protein Import Into Peroxisome Membrane Protein Stabilization Transmembrane Transport Chaperone-mediated Protein Folding Chaperone-mediated Protein Transport Establishment Of Protein Localization To Peroxisome Negative Regulation Of Lipid Binding
Pathways			ABC transporters in lipid homeostasis Class I peroxisomal membrane protein import Class I peroxisomal membrane protein import
Drugs
Diseases			Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Conotruncal heart defects (inherited effects) ( 28468790)
Interacting Genes		3 interacting genes: EXT2 GSK3A PEX19	38 interacting genes: ABCD1 ABCD2 ABCD3 BCL2L11 CDC25A CDKN2A EIF1B F11R FKBP7 GSKIP IFNB1 IL23A IRF3 KIFAP3 MFSD5 NAT8L OIP5 PEX10 PEX11A PEX11B PEX12 PEX13 PEX14 PEX16 PEX26 PEX3 PMP22 PPIB PSORS1C2 PXMP4 SLC25A17 SLC34A1 SMAD2 SRPK1 STK3 SUOX TMEM54 TXN2
Entrez ID		51527	5824
HPRD ID		16601	02610
Ensembl ID		ENSG00000100744	ENSG00000162735
Uniprot IDs		A0A024R6P6 Q9P0R6	A0A0S2Z497 P40855
PDB IDs		1SGO	2W85 2WL8 3AJB 3MK4 5LNF
Enriched GO Terms of Interacting Partners?
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