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RTCB and MIRLET7E
Data Source:
BioGRID
(unspecified method)
RTCB
MIRLET7E
Description
RNA 2',3'-cyclic phosphate and 5'-OH ligase
microRNA let-7e
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Intracellular Membrane-bounded Organelle
TRNA-splicing Ligase Complex
Extracellular Space
Molecular Function
RNA Binding
RNA Ligase (ATP) Activity
Protein Binding
GTP Binding
Vinculin Binding
Metal Ion Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
TRNA Exon Ligation Utilizing 2',3' Cyclic Phosphate Of 5'-exon As Source Of Linkage Phosphate
TRNA Splicing, Via Endonucleolytic Cleavage And Ligation
Negative Regulation Of Interleukin-6 Production
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of Interleukin-6-mediated Signaling Pathway
Negative Regulation Of Receptor Signaling Pathway Via STAT
Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Negative Regulation Of Signaling Receptor Activity
Pathways
tRNA processing in the nucleus
Drugs
Sucrose
Diseases
GWAS
Dimensional psychopathology (Arousal) (
29496196
)
Dimensional psychopathology (Negative) (
29496196
)
Interacting Genes
75 interacting genes:
CRK
ESR1
LINC01554
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
105 interacting genes:
AIMP1
AIMP2
APOBEC3B
AQR
ATXN2L
C1QBP
CDC40
CDC5L
CELF1
CHERP
CPSF1
CRTAP
DARS1
DDX1
DDX21
DDX23
DDX3X
DHX36
DHX37
EDC4
EIF2AK2
EPRS1
ERAL1
FAM98A
FAM98B
FUS
G3BP2
GRSF1
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
PDCD11
PGAM5
PLOD1
PLRG1
PRMT1
PTBP1
PUF60
PUM1
PUM2
PURA
QARS1
RARS1
RBFOX2
RBM10
RBM14
RBM4
RBM47
RBM5
RTCB
SART3
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
TUT7
U2SURP
UPF1
UTP20
XAB2
YBX1
YBX2
YBX3
ZFR
ZNF346
Entrez ID
51493
406887
HPRD ID
13695
Ensembl ID
ENSG00000100220
ENSG00000198972
Uniprot IDs
Q9Y3I0
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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