RNF138 and RAD51D

Data Source:
BioGRID (enzymatic study)

		RNF138	RAD51D
Description		ring finger protein 138	RAD51 paralog D
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Site Of Double-strand Break	Chromosome, Telomeric Region Nucleus Nucleoplasm Replication Fork Cytoplasm Centrosome Rad51B-Rad51C-Rad51D-XRCC2 Complex
	Molecular Function	Single-stranded DNA Binding Protein Binding Protein Kinase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Four-way Junction DNA Binding DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Gamma-tubulin Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Wnt Signaling Pathway Protein Ubiquitination Cellular Response To Leukemia Inhibitory Factor	Telomere Maintenance Via Recombination Telomere Maintenance Double-strand Break Repair Via Homologous Recombination DNA Repair Reciprocal Meiotic Recombination Interstrand Cross-link Repair Strand Invasion Regulation Of Cell Cycle
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Presynaptic phase of homologous DNA pairing and strand exchange TP53 Regulates Transcription of DNA Repair Genes
Drugs
Diseases
GWAS
Interacting Genes		15 interacting genes: APP CFAP206 EFEMP2 LNX2 NTAQ1 PCBP4 QKI RAD51D TAF9 TCF7L2 TRIM8 UBE2D2 UBE2D4 UBE2K UBE2W	49 interacting genes: AMOTL2 BLM C1orf94 CCDC33 CCNL1 CEP57L1 EFHC2 GEMIN4 HSF2BP IHO1 IKZF1 IKZF3 KATNBL1 KIFC3 KRT15 LIMS1 LNX1 LZTS2 MAPK8IP3 MEOX2 NFKBID PICK1 PNMA1 POLDIP3 PRDM14 PRDM6 RAD51B RAD51C RBM48 REL RHOU RNF138 SORBS3 SPATC1L STX11 SWSAP1 TCF4 TEPSIN TLE5 TRIM14 TTC23 VPS9D1 XRCC2 XRCC3 ZBTB42 ZC2HC1C ZNF343 ZNF774 ZSWIM7
Entrez ID		51444	5892
HPRD ID		11508	04261
Ensembl ID		ENSG00000134758	ENSG00000185379
Uniprot IDs		A0A140VJT9 Q8WVD3	O75771
PDB IDs			2KZ3
Enriched GO Terms of Interacting Partners?
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