TEX264 and CERS4

Data Source:
BioGRID (two hybrid)

		TEX264	CERS4
Description		testis expressed 264, ER-phagy receptor	ceramide synthase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Extracellular Region Nucleus Replication Fork Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane Platelet Alpha Granule Lumen	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Signaling Receptor Activity	DNA Binding Protein Binding N-acyltransferase Activity Sphingosine N-acyltransferase Activity
	Biological Process	Platelet Degranulation Reticulophagy Protein-DNA Covalent Cross-linking Repair	Sphingolipid Biosynthetic Process Ceramide Biosynthetic Process
Pathways		Platelet degranulation	Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS			Mean reticulocyte volume ( 32888494) Metabolite levels ( 31628463) Red cell distribution width ( 32888494) Refractive error ( 32231278) Serum metabolite ratios in chronic kidney disease ( 29545352) Sphingolipid levels ( 26068415) Sphingomyelin levels ( 31551469) Thyroid stimulating hormone levels ( 30367059 32769997) Very long-chain saturated fatty acid levels (fatty acid 24:0) ( 25378659)
Interacting Genes		28 interacting genes: ADGRG3 ARL13B CERS4 CLDN2 CLN6 COQ9 CREB3L1 EMP1 FAM209A FFAR2 FFAR3 GABARAPL2 GJB1 GPR152 GPR42 LHFPL4 LHFPL5 MFF MS4A3 NKX3-1 OPRM1 SLC10A2 SLC34A2 SMIM3 TM4SF18 TMEM31 TMEM79 TSPAN12	47 interacting genes: C1QL4 CCL4L2 CLEC1A COL4A5 CTXN3 CXCL16 CYB5R3 EMD FATE1 FCER1G FXYD6 FXYD6-FXYD2 GPR151 IER3IP1 IGFBP5 ITGAM JAGN1 LHFPL5 MS4A1 NAT8 NEU1 PLP2 PNLIPRP1 PTPN9 SCAMP5 SCD SERF1A SERF1B SERP2 SLC13A4 SLC29A2 SLC35A1 SLC35F6 SLC7A1 SMIM11A SMIM11B STX7 STX8 TEX264 TMEM119 TMEM176A TMEM254 TMEM72 TOMM6 TSPO2 UPK1B VAMP2
Entrez ID		51368	79603
HPRD ID		15492	13962
Ensembl ID		ENSG00000164081	ENSG00000090661
Uniprot IDs		A0A087WTU3 Q9Y6I9	Q53HF9 Q9HA82
PDB IDs
Enriched GO Terms of Interacting Partners?
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