TEX264 and GJB1

Data Source:
BioGRID (two hybrid)

		TEX264	GJB1
Description		testis expressed 264, ER-phagy receptor	gap junction protein beta 1
Image		No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Extracellular Region Nucleus Replication Fork Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane Platelet Alpha Granule Lumen	Endoplasmic Reticulum Membrane Connexin Complex Integral Component Of Membrane
	Molecular Function	Protein Binding Signaling Receptor Activity	Gap Junction Channel Activity Protein Binding
	Biological Process	Platelet Degranulation Reticulophagy Protein-DNA Covalent Cross-linking Repair	Cell-cell Signaling Nervous System Development Gap Junction Assembly Transmembrane Transport
Pathways		Platelet degranulation	Oligomerization of connexins into connexons Oligomerization of connexins into connexons Transport of connexins along the secretory pathway Gap junction assembly
Drugs
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS
Interacting Genes		28 interacting genes: ADGRG3 ARL13B CERS4 CLDN2 CLN6 COQ9 CREB3L1 EMP1 FAM209A FFAR2 FFAR3 GABARAPL2 GJB1 GPR152 GPR42 LHFPL4 LHFPL5 MFF MS4A3 NKX3-1 OPRM1 SLC10A2 SLC34A2 SMIM3 TM4SF18 TMEM31 TMEM79 TSPAN12	57 interacting genes: APOL3 APP BMP10 C1GALT1 C2CD2L C3orf52 CALM1 CD37 CD79A CDIPT CLEC7A CMTM3 CMTM5 CNST COMT CTXN3 CXCL9 EFNA5 EGFR EMP3 EPHA1 GJB2 GLP1R GPR25 IER3IP1 ITGAM LAT LHFPL2 MAL MAL2 MFF MS4A13 MST1R NDUFB11 NIPAL4 PRKACA PRKCA PTPN2 PTPN9 RTP2 SCD SERTM1 SLC12A7 SRC STX8 TEX264 TF TM4SF4 TMEM120B TMEM14C TMEM19 TMEM218 TMEM98 UPK1B VEGFA VKORC1 YIPF6
Entrez ID		51368	2705
HPRD ID		15492	02367
Ensembl ID		ENSG00000164081	ENSG00000169562
Uniprot IDs		A0A087WTU3 Q9Y6I9	A0A654ICJ7 P08034
PDB IDs			1TXH 5KK9
Enriched GO Terms of Interacting Partners?
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