MS4A4A and CMTM7

Data Source:
BioGRID (two hybrid)

		MS4A4A	CMTM7
Description		membrane spanning 4-domains A4A	CKLF like MARVEL transmembrane domain containing 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Membrane Plasma Membrane Raft	Extracellular Space Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Cytokine Activity Protein Binding
	Biological Process		B-1a B Cell Differentiation Chemotaxis Signal Transduction
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 21460841) Alzheimer's disease in APOE e4- carriers ( 25778476) C-reactive protein levels ( 30388399) Cerebrospinal fluid sTREM-2 levels ( 31413141) Fibrinogen levels ( 28107422)	Copper levels ( 26025379) Hallux valgus ( 32131869) IgM levels ( 28628107) Metabolite levels ( 23823483) Mortality in heart failure ( 20400778) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		14 interacting genes: ATP6V0E1 CLDN19 CMTM7 LPAR3 MAL NRG1 PLP1 RPRM RUSF1 SEC22A SERTM1 TMEM14B TMUB2 UPK1B	47 interacting genes: ADTRP AGER AQP6 ARL13B B3GAT1 BIK BSCL2 CD74 CD79A CLSTN3 CREB3L1 DAGLA DNAJC1 ELOVL4 FAM174A FAM209A FFAR2 FRMD3 GGT7 GORAB HAS3 HIBADH HSD17B13 LDLRAD1 LHFPL5 LMNA MS4A4A MUC1 PAGE1 PIANP PSMD6 RETREG3 SDC3 SHISA3 SLC14A2 SLC30A8 SSMEM1 STX1A TCTA TEX29 THAP4 TMEM106C TMEM174 TMEM31 TMPRSS2 TMX2 TNFRSF17
Entrez ID		51338	112616
HPRD ID		08408	06988
Ensembl ID		ENSG00000110079	ENSG00000153551
Uniprot IDs		A0A384MDW1 Q4JF27 Q96JQ5	F8WDZ3 Q96FZ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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