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CDK17 and PRKACG
Data Source:
BioGRID
(two hybrid)
CDK17
PRKACG
Description
cyclin dependent kinase 17
protein kinase cAMP-activated catalytic subunit gamma
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Nucleus
Nucleoplasm
Cytosol
Ciliary Base
Molecular Function
Protein Kinase Activity
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
AMP-activated Protein Kinase Activity
CAMP-dependent Protein Kinase Activity
Protein Binding
ATP Binding
Protein Kinase A Regulatory Subunit Binding
Biological Process
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Protein Phosphorylation
Regulation Of Cell Cycle
Stimulatory C-type Lectin Receptor Signaling Pathway
Renal Water Homeostasis
Protein Phosphorylation
Spermatogenesis
Blood Coagulation
Male Gonad Development
Protein Kinase A Signaling
Activation Of Protein Kinase A Activity
High-density Lipoprotein Particle Assembly
Cellular Response To Glucagon Stimulus
Pathways
PKA-mediated phosphorylation of CREB
PKA-mediated phosphorylation of key metabolic factors
Triglyceride catabolism
PKA activation
PKA activation in glucagon signalling
DARPP-32 events
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Rap1 signalling
Regulation of insulin secretion
Vasopressin regulates renal water homeostasis via Aquaporins
VEGFA-VEGFR2 Pathway
CREB1 phosphorylation through the activation of Adenylate Cyclase
CREB1 phosphorylation through the activation of Adenylate Cyclase
Degradation of GLI1 by the proteasome
Degradation of GLI2 by the proteasome
GLI3 is processed to GLI3R by the proteasome
Hedgehog 'off' state
CD209 (DC-SIGN) signaling
MAPK6/MAPK4 signaling
RET signaling
HDL assembly
ROBO receptors bind AKAP5
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
ADORA2B mediated anti-inflammatory cytokines production
ADORA2B mediated anti-inflammatory cytokines production
FCGR3A-mediated IL10 synthesis
FCGR3A-mediated IL10 synthesis
Factors involved in megakaryocyte development and platelet production
Drugs
Fostamatinib
Diseases
GWAS
Diastolic blood pressure (
30224653
)
Manganese levels (
26025379
)
Phospholipid levels (plasma) (
22359512
)
Metabolite levels (
23823483
)
Night sleep phenotypes (
27126917
)
Interacting Genes
12 interacting genes:
APP
BICDL2
CDKN2B
DPY30
EPHA2
PRKACG
TDRD7
TGFBR1
UBC
YWHAG
YWHAQ
YWHAZ
5 interacting genes:
CDK17
CETP
HMGN1
TNP1
TNP2
Entrez ID
5128
5568
HPRD ID
09141
01483
Ensembl ID
ENSG00000059758
ENSG00000165059
Uniprot IDs
A0A024RBH0
Q00537
P22612
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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