CDKL3 and ZBTB14

Data Source:
BioGRID (two hybrid)

		CDKL3	ZBTB14
Description		cyclin dependent kinase like 3	zinc finger and BTB domain containing 14
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Nucleolus Cytosol Aggresome
	Molecular Function	Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cellular Protein Modification Process Protein Phosphorylation Negative Regulation Of Axon Extension Positive Regulation Of Dendrite Morphogenesis Regulation Of Cell Cycle Dendrite Extension	Negative Regulation Of Transcription By RNA Polymerase II Kidney Development Heart Valve Development Cardiac Septum Development Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Coronary Vasculature Development
Pathways
Drugs
Diseases
GWAS		Eosinophil counts ( 27863252) Moderate-to-late spontaneous preterm birth ( 31194736)	Cerebral amyloid deposition (PET imaging) ( 26252872)
Interacting Genes		31 interacting genes: APP ATG4A CYSRT1 DISC1 DNAAF6 FXR1 FXR2 GGA1 GOLGA2 IKZF1 KANK2 KASH5 KRTAP10-9 LRP2BP LRRK2 LZTS2 MCC MDFI MTUS2 PICK1 PIH1D2 RABEP1 SNRNP70 SRPK1 TRIM27 TRIM37 TTF2 ZBTB14 ZBTB43 ZBTB8A ZRANB1	50 interacting genes: AP1M1 ATP5PO ATRIP BAZ2B BYSL C2orf68 CAPN6 CBX8 CDK16 CDKL3 CEP19 DDX6 EAF1 EIF1AD ENKD1 EPM2AIP1 FAM161A FAM90A1 GORASP2 INTS3 KAT5 MAD2L1BP MFAP1 MORF4L2 MRPL11 NAA10 NAA11 PIN1 PNKP POLR2L PRMT1 RNASEH2B RNPS1 RPA1 RPA2 RPL9 RPS25 RPS7 SCNM1 SDCBP SNRPB2 SYT16 TCEANC TRIM55 TSTD2 TXN2 WNT9A ZBTB21 ZCCHC10 ZMAT2
Entrez ID		51265	7541
HPRD ID		09766	03674
Ensembl ID		ENSG00000006837	ENSG00000198081
Uniprot IDs		B4DX41 Q8IVW4	B2R850 O43829
PDB IDs		3ZDU
Enriched GO Terms of Interacting Partners?
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