MRNIP and DUSP23

Data Source:
BioGRID (two hybrid)

		MRNIP	DUSP23
Description		MRN complex interacting protein	dual specificity phosphatase 23
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mre11 Complex	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Chromatin Binding Protein Binding	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	DNA Repair Cellular Response To DNA Damage Stimulus Mitotic G2 DNA Damage Checkpoint Response To Ionizing Radiation Positive Regulation Of Protein Kinase Activity Protein Localization To Chromatin Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair Via Nonhomologous End Joining	Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs			4-Nitrophenyl Phosphate
Diseases
GWAS			Bone mineral density (Ward's triangle area) ( 27397699) C-reactive protein ( 22939635) Interstitial lung disease ( 21787189)
Interacting Genes		9 interacting genes: DUSP23 EFHC1 EIF3E ENKD1 NUTF2 NXF1 PICK1 PKIA PSMB1	32 interacting genes: ASB13 ASB6 BANF2 CCDC186 CEP126 DBI DBN1 DDIT4L DNMT3B EDRF1 EED EXOSC8 GCM1 KAT5 KBTBD7 MKRN1 MRNIP MRPL20 MTFR1 NIF3L1 PRDX4 PSMB8 PSME2 RPL8 RUFY2 SHC1 SMPD1 TCF4 TMOD3 TUBA1A UBA3 ZNF746
Entrez ID		51149	54935
HPRD ID		17420	07908
Ensembl ID		ENSG00000161010	ENSG00000158716
Uniprot IDs		Q6NTE8	A0A140VJI5 Q9BVJ7
PDB IDs			2IMG 4ERC
Enriched GO Terms of Interacting Partners?
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